Rochester, Minnesota




Hongfang Liu, Ph.D., is a professor of biomedical informatics in the Mayo Clinic College of Medicine, and is a consultant in the Department of Health Sciences Research at Mayo Clinic. As a researcher, she is leading Mayo Clinic's clinical natural language processing (NLP) program with the mission of providing support to access clinical information stored in unstructured text for research and practice. Administratively, Dr. Liu serves as the section head for Medical Informatics in the Division of Biomedical Statistics and Informatics.

Focus areas

Dr. Liu's primary research interest is in biomedical NLP and data normalization. She has been developing a suite of open-source NLP systems for accessing clinical information, such as medications or findings from clinical notes. Additionally, she has been conducting collaborative research in the past decade in utilizing existing knowledge bases for high-throughput omics profiling data analysis and functional interpretation.

Significance to patient care

Dr. Liu's work in informatics has resulted in informatics systems that unlock clinical information stored in clinical narratives. Her work accelerates the pace of knowledge discovery, implementation and delivery for improved health care.

Professional highlights

  • Leader, American Medical Informatics Association Natural Language Processing (NLP) Working Group, 2014-present
  • Member, Informatics Domain Task Force, national CTSA Consortium, 2015-present


See my publications


Primary Appointment

  1. Consultant, Division of Biomedical Statistics and Informatics, Department of Health Sciences Research

Academic Rank

  1. Professor of Biomedical Informatics


  1. Doctor of Philosophy - Computer Science Specialized in Biomedical Informatics Graduate School, City University of New York
  2. Master of Science - Computer Science Fordham University
  3. Completion of Graduate Study in Combinatorics The University of Science & Technology of China
  4. BS - Applied Mathematics and Statistics The University of Science & Technology of China

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