Location

Rochester, Minnesota

Contact

Dudakovic.Amel@mayo.edu

SUMMARY

Research undertaken by Amel Dudakovic, Ph.D., is focused on advancing the health of patients affected by musculoskeletal conditions. Specifically, his studies aim to identify molecular events that can be targeted to address bone, cartilage and fibrotic conditions. To achieve this goal, Dr. Dudakovic uses his background in molecular and cell biology to understand the basis of human disease and then applies his pharmacology training to identify suitable cell-based and pharmacological strategies to prevent and combat these musculoskeletal ailments.

Focus areas

  • Bone development and disease. Dr. Dudakovic seeks to define mechanisms, including epigenetic events, that govern bone development and diseases associated with this dynamic tissue.
  • Arthrofibrosis. Dr. Dudakovic is working to establish causes of arthrofibrosis, a relatively common complication following total knee arthroplasty, as well as to develop prevention and treatment strategies.
  • Tissue regeneration. Developing cell-based and pharmacological strategies to regenerate damaged musculoskeletal tissues is a key focus area for Dr. Dudakovic.

Significance to patient care

Musculoskeletal diseases have significant health and economic impacts. The burden of treating musculoskeletal disease is expected to increase in the future as populations age. Dr. Dudakovic's studies aim to gain insight into and define the mechanisms that contribute to musculoskeletal tissue formation and degeneration. An enhanced understanding of these processes may decrease the impact of musculoskeletal diseases by helping researchers design strategies that can prevent and restore damaged tissues.

Professional highlights

  • Career Development Award in Orthopedics Research, 2019-2021
  • Ruth L. Kirschstein Postdoctoral Individual National Research Service F32 Award, National Cancer Institute, 2015-2018
  • John Haddad Young Investigator Award, American Society for Bone and Mineral Research (ASBMR), 2017
  • Harold M. Frost Young Investigator Award, ASBMR, 2015

PROFESSIONAL DETAILS

Administrative Appointment

  1. Associate Consultant I-Research, Department of Orthopedic Surgery

Academic Rank

  1. Assistant Professor of Biochemistry and Molecular Biology
  2. Assistant Professor of Orthopedics

EDUCATION

  1. PhD - Pharmacology University of Iowa College of Medicine
  2. BS - Biochemistry St. Cloud State University
  3. AA Rochester Community and Technical College
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BIO-20418133

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