Publications

  1. Melenovsky V, Hoskova E, Velebova K, Veleba J, Borlaug BA, Benes J, Kuda O, Cajka T, Segetova M, Thieme L, Kopecky J Jr, Kopecky J Sr, Pelikanova T, Haluzik M, Hill M, Kahleova H. Metformin Improves Glycemic Control and Postprandial Metabolism and Enhances Postprandial Glucagon-Like Peptide 1 Secretion in Patients With Type 2 Diabetes and Heart Failure: A Randomized, Double-Blind, Placebo-Controlled Trial. Clin Diabetes. 2025 Winter; 43 (1):23-32 Epub 2024 Sept 09
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  2. Packer M, Lam CSP, Butler J, Zannad F, Vaduganathan M, Borlaug BA. Is Type 2 Diabetes a Modifiable Risk Factor for the Evolution and Progression of Heart Failure With a Preserved Ejection Fraction? J Am Coll Cardiol. 2025 Sep 17 Epub 2025 Sept 17
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  3. Pandey A, Kitzman DW, Chinnakondepalli KM, Patel S, Borlaug BA, Butler J, Davies MJ, Shah SJ, Verma S, Ronnback C, Domdey A, Liisberg K, Schou M, Perna E, Ahmed FZ, Fu M, Petrie MC, Kosiborod MN. Frailty and Effects of Semaglutide in Obesity-Related HFpEF: Findings From the STEP-HFpEF Program. JACC Heart Fail. 2025 Sep 15; 102610 Epub 2025 Sept 15
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  4. Packer M, Zile MR, Kramer CM, DiMaria JM, Baum SJ, Litwin SE, Murakami M, Zhou C, Ou Y, Koeneman L, Borlaug BA, SUMMIT Trial Study Group. Influence of Type 2 Diabetes on the Effects of Tirzepatide in Patients With Heart Failure and a Preserved Ejection Fraction With Obesity: A Prespecified Stratification-Based Analysis. J Am Coll Cardiol. 2025 Sep 9; 86 (10):696-707
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  5. Egbe AC, Reddy YNV, Pellikka PA, Borlaug BA. Impaired Pulmonary Vascular Reserve in Adults with Repaired Coarctation of Aorta: Prevalence, Correlates, and Association with Disease Severity. J Am Soc Echocardiogr. 2025 Sep 5 Epub 2025 Sept 05
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  6. Popovic D, Reddy YNV, Omar M, Omote K, Melenovsky V, Burkhoff D, Borlaug BA. Acute Effects of Myeloperoxidase Inhibition on Exercise Hemodynamics in Heart Failure With Preserved Ejection Fraction: A Randomized Clinical Trial. Mayo Clin Proc. 2025 Sep; 100 (9):1495-1505 Epub 2025 Aug 06
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  7. Egbe AC, Miranda WR, Jain C, Connolly HM, Burchill LJ, Borlaug BA. Prognostic value of right ventricular-pulmonary arterial coupling in adults with repaired coarctation of aorta. Int J Cardiol Congenit Heart Dis. 2025 Sep; 21:100608 Epub 2025 July 03
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  8. Yaku H, Sauer AJ, Patel S, O'Keefe EL, Borlaug BA, Kitzman DW, Windsor SL, Khumri T, Umpierrez G, Kosiborod MN, Shah SJ. Orthostatic Pulse Pressure as a Potential Indicator of Preload Insufficiency in HFpEF: Insights From PRESERVED-HF. JACC Heart Fail. 2025 Sep; 13 (9):102566 Epub 2025 July 25
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  9. Chaudhary RS, Hussain SMD, Wang YS, Komtebedde J, Hasenfuss G, Borlaug BA, Kaye DM, Cleland JGF, Leon MB, Shah SJ, van Veldhuisen DJ, Solomon SD, Cikes M, Cutlip DE. Expanded Definition of Worsening Heart Failure: Impact on Clinical Outcomes and Quality-of-Life Assessment. JACC Heart Fail. 2025 Sep; 13 (9):102571 Epub 2025 July 25
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  10. Reddy YNV, Asokan AK, Frantz RP, Hemnes A, Hassoun PM, Barnard J, Horn E, Leopold JA, Rischard F, Rosenzweig EB, Hill NS, Erzurum SC, Beck GJ, Finet JE, Grunig G, Jellis CL, Mathai SC, Simpson CE, Tang WHW, Nair KS, Borlaug BA. Metabolomic Evidence of Biological Overlap with Heart Failure with Preserved Ejection Fraction in a Subset of Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2025 Sep; 211 (9):1701-1713
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  11. Egbe AC, Abozied O, Abdelhalim AT, ElZalabany S, Kholeif Z, Reddy YNV, Borlaug BA. Feasibility, Reproducibility, and Prognostic Value of Exercise Echocardiography for Cardiac Output Reserve Assessment in Fontan Physiology. Circ Heart Fail. 2025 Sep; 18 (9):e012908 Epub 2025 Aug 26
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  12. Borlaug BA, Zile MR, Kramer CM, Litwin SE, Ye W, Ou Y, Hurt K, Murakami M, Packer M. HFpEF-ABA score is a more useful enrichment tool than natriuretic peptides in heart failure with preserved ejection fraction. Eur Heart J. 2025 Aug 31 [Epub ahead of print]
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  13. Borlaug BA, Testani JM, Petrie MC, Wang Z, Cunningham J, Adams KF Jr, Amir O, Belohlavek J, Bocchi E, Freitas A Jr, Hominal M, Kadokami T, Merkely B, Miller CA, Nunez J, Verma S, Yilmaz MB, Oru E, Sam F. Effects of volenrelaxin in worsening heart failure with preserved ejection fraction: a phase 2 randomized trial. Nat Med. 2025 Aug 31 [Epub ahead of print]
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  14. Crum Y, van Veldhuisen DJ, Shah SJ, Mylavarapu U, Hu M, Komtebedde J, Lobeek M, Hoendermis ES, Litwin SE, Solomon SD, Cutlip DE, Leon MB, Kaye D, Bruch L, Seidler T, Cikes M, Mohan R, Lilly S, Collins N, Emani S, Chetcuti S, Bugger H, Kotlyar E, Reed GW, Gordon R, Gupta DK, Borlaug BA, Gorter TM. Epicardial adipose tissue, functional status and invasive hemodynamics in heart failure with preserved ejection fraction. JACC Adv. 2025 Aug 26; 102185 [Epub ahead of print]
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  15. Egbe AC, Abozied O, Abdelhalim AT, Jain CC, Miranda WR, Kholeif Z, Connolly HM, Borlaug BA. Relationship between left atrial stiffness, pulmonary congestion, and impaired aerobic capacity in adults with repaired coarctation of aorta. Am Heart J. 2025 Aug 21; 291:89-100 [Epub ahead of print]
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  16. Berg-Hansen K, Tinggaard AB, Nielsen R, Jensen TH, Gopalasingam N, Larsen AH, Moller N, Bottcher M, Hollingdal M, Poulsen MK, Antonsen L, Kondo T, Jhund PS, Borlaug BA, Mebazaa A, Moller JE, Vraa S, Grand J, Hove JD, Wolsk E, Schou M, Wiggers H. Should Exogenous Ketone Body Supplementation Be Considered in Patients Hospitalized for Acute Heart Failure? Rationale and Design of the KETO-AHF Trial. J Card Fail. 2025 Aug 9 Epub 2025 Aug 09
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  17. Fazzini L, Padkins MR, Berg-Hansen K, Gori M, Kane GC, Hillerson DB, Tavazzi G, Reddy YNV, Jae OK, Borlaug B, Jentzer JC. Left ventricular-arterial coupling and mortality in the cardiac intensive care unit. Eur Heart J Acute Cardiovasc Care. 2025 Aug 6; 14 (7):394-402
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  18. Ibe T, Reddy YNV, Harada T, Doi S, Tada A, Naser JA, Demmer RT, Borlaug BA. Utility of HFpEF Diagnostic Scores to Stratify Cardiac Reserve Among Patients With Dyspnea. JACC Heart Fail. 2025 Aug 5; 13 (10):102526 Epub 2025 Aug 05
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  19. Reddy YNV, Frantz RP, Hassoun PM, Hemnes A, Horn E, Leopold JA, Rischard F, Rosenzweig EB, Hill NS, Erzurum SC, Beck GJ, Finet JE, Jellis CL, Mathai SC, Mehra R, Tang WHW, Borlaug BA, PVDOMICS Study Group. Left Heart Abnormalities in Patients With Lung Disease, OSA, and Chronic Thromboemboli at Risk for or With Known Pulmonary Hypertension. Circ Heart Fail. 2025 Aug; 18 (8):e012912 Epub 2025 May 29
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  20. Borlaug BA, Zile MR, Kramer CM, Ye W, Ou Y, Hurt K, Murakami M, Packer M, SUMMIT Trial Study Group. Impact of Body Mass Index, Central Adiposity, and Weight Loss on the Benefits of Tirzepatide in HFpEF: The SUMMIT Trial. J Am Coll Cardiol. 2025 Jul 29; 86 (4):242-255
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  21. Padmanabhan Menon D, Frantz RP, Gochanour BR, Beck GJ, Berman-Rosenzweig ES, Borlaug BA, Erzurum SC, Farha S, Finet JE, Grunig G, Hassoun PM, Hemnes AR, Hill NS, Horn EM, Lempel JK, Leopold JA, Mathai SC, Renapurkar RD, Rischard FP, Waxman AB, DuBrock HM. Ground Glass Opacities in Pulmonary Arterial Hypertension-Results from the PVDOMICS Study. Ann Am Thorac Soc. 2025 Jul 18 Epub 2025 July 18
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  22. Anand V, Scott CG, Ali K, Nkomo VT, Thaden JJ, Kane GC, Borgeson DD, Borlaug BA, Pislaru C, Eleid MF, Crestanello JA, Pellikka PA, Pislaru SV. Association of Diuretic Dosage With Outcomes in Patients With Hemodynamically Significant Isolated Tricuspid Valve Regurgitation. J Am Heart Assoc. 2025 Jul 15; 14 (14):e039989 Epub 2025 July 14
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  23. Lewis GD, Tada A, Landsteiner I, Borlaug BA. Physiologic phenotyping of responses to exercise and activity in heart failure. Circulation Research. 2025 Jul 7; 137 (2):290-315
  24. Yaku H, Burkhoff D, Borlaug BA, Lala A, Butler J, Rich S, Shah SJ. Oral Levosimendan for the Treatment of Pulmonary Hypertension due to Heart Failure With Preserved Ejection Fraction: Rationale and Design of the LEVEL Trial. J Card Fail. 2025 Jul 7 Epub 2025 July 07
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  25. Ng ACT, Dong X, Koepp KE, Obokata M, Sorimachi H, Galloway G, Araoz P, Delgado V, Bax JJ, Borlaug BA. Sexual dimorphism in the relationships between intramyocardial fat, myocardial fibrosis, and exercise intolerance in heart failure with preserved ejection fraction. Eur J Heart Fail. 2025 Jul; 27 (7):1359-1361 Epub 2024 Sept 24
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  26. Donisan T, Inglis S, Asirvatham SJ, Borlaug BA. Atrioventricular Dyssynchrony and Dyspnea in Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2025 Jul; 18 (7):e013183 Epub 2025 May 19
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  27. Ibe T, Demmer RT, Harada T, Doi S, Tada A, Naser JA, Reddy YNV, Borlaug BA. Prognostic significance of unintentional weight loss in heart failure with preserved ejection fraction. Eur J Heart Fail. 2025 Jun 26 Epub 2025 June 26
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  28. Doi S, Tada A, Harada T, Naser JA, Ibe T, Smith JR, Reddy YNV, Borlaug BA. Determinants of submaximal exercise intolerance in patients with heart failure and preserved ejection fraction: Insights from the lactate threshold. Eur J Heart Fail. 2025 Jun 18 Epub 2025 June 18
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  29. Inciardi RM, Vaduganathan M, Claggett B, AbouEzzeddine OF, Borlaug BA, Desai AS, Jhund PS, Lam CSP, Minamisawa M, Lewis EF, Redfield MM, Shah SJ, Fontana M, Pfeffer MA, McMurray JJV, Solomon SD. Application of a transthyretin amyloid cardiomyopathy score to heart failure with mildly reduced or preserved ejection fraction. Eur J Heart Fail. 2025 Jun 9 Epub 2025 June 09
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  30. Ambrosy AP, Sauer AJ, Patel S, Windsor SL, Borlaug BA, Husain M, Inzucchi SE, Kitzman DW, McGuire DK, Shah SJ, Sharma K, Umpierrez G, Kosiborod MN. Baseline kidney function and the effects of dapagliflozin on health status in heart failure in DEFINE-HF and PRESERVED-HF. ESC Heart Fail. 2025 Jun; 12 (3):1676-1681 Epub 2024 Dec 24
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  31. Pandey A, Lewis GD, Borlaug BA, Shah SJ, Sauer AJ, Litwin S, Sharma K, Jorkasky DK, Tarka EA, Khan SM, Kitzman DW. Novel Controlled Metabolic Accelerator for Obesity-Related HFpEF: The HuMAIN-HFpEF Randomized Clinical Trial. JAMA Cardiol. 2025 Jun 1; 10 (6):609-616
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  32. Fioretti F, Nair AP, Anker SD, Borlaug BA, Kereiakes DJ, Lindenfeld J, Stone GW, Butler J. Therapeutic left-to-right shunting in heart failure. Eur Heart J. 2025 May 14; 46 (19):1787-1802
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  33. Packer M, Zile MR, Kramer CM, Murakami M, Ou Y, Borlaug BA, SUMMIT Trial Study Group. Interplay of Chronic Kidney Disease and the Effects of Tirzepatide in Patients With Heart Failure, Preserved Ejection Fraction, and Obesity: The SUMMIT Trial. J Am Coll Cardiol. 2025 May 13; 85 (18):1721-1735 Epub 2025 Mar 31
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  34. Reddy YNV, Frantz RP, Hemnes AR, Hassoun PM, Horn E, Leopold JA, Rischard F, Rosenzweig EB, Hill NS, Erzurum SC, Beck GJ, Finet JE, Jellis CL, Mathai SC, Tang WHW, Borlaug BA, PVDOMICS Study Group. Disentangling the Impact of Adiposity From Insulin Resistance in Heart Failure With Preserved Ejection Fraction. J Am Coll Cardiol. 2025 May 13; 85 (18):1774-1788
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  35. Bianchettin RG, Gawey BJ, Acosta AJ, Borlaug BA, Caples SM, Collazo-Clavell ML, Clark MM, Lara-Breitinger KM, Lerman A, Lerman LO, Madhavan M, Schwartz GL, Terzic CM, Lopez-Jimenez F. Clinical Assessment of People With Obesity: Focus on Adiposity-Related Multimorbidity. Mayo Clin Proc. 2025 May 5 Epub 2025 May 05
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  36. Naser JA, Massad F, Scott CG, Borlaug BA, Michelena HI, Simard TJ, Siontis KC, Kennedy AM, Thaden JJ, Pellikka PA, Nkomo VT, Eleid MF, Pislaru SV. Clinical Outcomes of Mitral Regurgitation Severity and Transcatheter Edge-to-Edge Repair in Atrial Functional Mitral Regurgitation. Catheter Cardiovasc Interv. 2025 May 4 Epub 2025 May 04
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  37. Doi S, Reddy YNV, Jensen MD, Smith JR, Borlaug BA. Dapagliflozin and ventilatory control during exercise in heart failure with preserved ejection fraction: the CAMEO-DAPA trial. Eur Heart J. 2025 Apr 22; 46 (16):1554-1556
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  38. Reddy YNV, Tada A, Obokata M, Carter RE, Kaye DM, Handoko ML, Andersen MJ, Sharma K, Tedford RJ, Redfield MM, Borlaug BA. Evidence-Based Application of Natriuretic Peptides in the Evaluation of Chronic Heart Failure With Preserved Ejection Fraction in the Ambulatory Outpatient Setting. Circulation. 2025 Apr 8; 151 (14):976-989 Epub 2025 Jan 22
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  39. Naser JA, Rahme SJ, Ibrahim H, Scott CG, Michelena HI, Borlaug BA, Kennedy AM, Eleid MF, Nkomo VT, Pellikka PA, Enriquez-Sarano M, Pislaru SV. Role of Quantitative Assessment of Atrial Functional Mitral Regurgitation. J Am Soc Echocardiogr. 2025 Apr; 38 (4):353-355 Epub 2024 Dec 15
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  40. Sorimachi H, Obokata M, Omote K, Reddy YNV, Burkhoff D, Shah SJ, Borlaug BA. Racial Differences of Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction. J Card Fail. 2025 Apr; 31 (4):624-634 Epub 2024 Aug 23
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  41. Younis A, Reddy YNV, Miranda WR, Abdelhalim AT, Borlaug BA, Connolly HM, Egbe AC. Temporal changes in prevalence and severity of pulmonary hypertension, and relationship to outcomes in coarctation of aorta. Int J Cardiol Heart Vasc. 2025 Apr; 57:101626 Epub 2025 Feb 07
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  42. Egbe AC, Reddy YNV, Miranda WR, Jain CC, Connolly HM, Borlaug BA. Hemodynamics of Exercise-Induced Hypertension and Relationship to Outcomes in Adults With Coarctation of the Aorta. Circ Heart Fail. 2025 Apr; 18 (4):e012459 Epub 2025 Mar 05
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  43. Naser JA, Ibrahim H, Andi K, Scott CG, Pellikka PA, Kennedy AM, Connolly HM, Nkomo VT, Enriquez-Sarano M, Pislaru SV, Warnes CA, Jain CC, Borlaug BA, Egbe AC. Prevalence, aetiology, and outcomes of native pulmonary regurgitation in the general adult population. Eur Heart J Cardiovasc Imaging. 2025 Mar 27; 26 (4):695-702
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  44. Zile MR, Borlaug BA, Kramer CM, Baum SJ, Litwin SE, Menon V, Ou Y, Weerakkody GJ, Hurt KC, Kanu C, Murakami M, Packer M, SUMMIT Trial Study Group. Effects of Tirzepatide on the Clinical Trajectory of Patients With Heart Failure, Preserved Ejection Fraction, and Obesity. Circulation. 2025 Mar 11; 151 (10):656-668 Epub 2024 Nov 18
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  45. Davies MJ, van der Meer P, Verma S, Patel S, Chinnakondepalli KM, Borlaug BA, Butler J, Kitzman DW, Shah SJ, Harring S, Salsali A, Rasmussen S, von Lewinski D, Abhayaratna W, Petrie MC, Kosiborod MN, STEP-HFpEF Trials Committees and Investigators. Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline HbA(1c) levels (STEP-HFpEF DM): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial. Lancet Diabetes Endocrinol. 2025 Mar; 13 (3):196-209 Epub 2025 Jan 20
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  46. Cao JJL, Miranda WR, Borlaug BA, Reddy YNV. Pseudo-Severe Mitral Stenosis From Obesity-Related HFpEF and Atrial Myopathy. Circ Heart Fail. 2025 Mar; 18 (3):e012703 Epub 2025 Jan 28
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  47. Farha S, Asosingh K, Hassoun PM, Barnard J, Comhair S, Reichard A, Wanner N, Radeva M, Aldred MA, Beck GJ, Berman-Rosenzweig E, Borlaug BA, Finet JE, Frantz RP, Grunig G, Hemnes AR, Hill N, Horn EM, Jellis C, Leopold JA, Mehra R, Park MM, Rischard FP, Tang WHW, Erzurum SC, PVDOMICS Study Group. Alterations in Mitochondrial Function in Pulmonary Vascular Diseases. Antioxid Redox Signal. 2025 Mar; 42 (7-9):361-377 Epub 2024 Dec 10
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  48. Davies MJ, van der Meer P, Verma S, Patel S, Chinnakondepalli KM, Borlaug BA, Butler J, Kitzman DW, Shah SJ, Harring S, Salsali A, Rasmussen S, von Lewinski D, Abhayaratna W, Petrie MC, Kosiborod MN. Semaglutide in obesity-related heart failure with preserved ejection fraction and type 2 diabetes across baseline hba levels (step-hfpef dm): a prespecified analysis of heart failure and metabolic outcomes from a randomised, placebo-controlled trial 1c. Lancet Diabetes & Endocrinology. 2025 Mar; 13 (3):196-209
  49. Shah SJ, Bonderman D, Borlaug BA, Cleland JGF, Lack G, Lu W, Voors AA, Zannad F, Gladwin MT. Macitentan for Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Pulmonary Vascular Disease: Results of the SERENADE Randomized Clinical Trial and Open-Label Extension Study. Circ Heart Fail. 2025 Mar; 18 (3):e011381 Epub 2025 Mar 11
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  50. Kramer CM, Borlaug BA, Zile MR, Ruff D, DiMaria JM, Menon V, Ou Y, Zarante AM, Hurt KC, Murakami M, Packer M, SUMMIT Trial Study Group. Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure: SUMMIT CMR Substudy. J Am Coll Cardiol. 2025 Feb 25; 85 (7):699-706 Epub 2024 Nov 18
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  51. Opp DN, Jain CC, Egbe AC, Borlaug BA, Reddy YV, Connolly HM, Lara-Breitinger KM, Cordina R, Miranda WR. Fontan haemodynamics in adults with obesity compared with overweight and normal body mass index: a retrospective invasive exercise study. Eur J Prev Cardiol. 2025 Feb 18; 32 (3):221-230
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  52. Salah HM, Fudim M, Borlaug BA, Litwin SE, Stark M, Shah SJ, Burkhoff D. Changes in Stressed Blood Volume With Endovascular Ablation of the Right Greater Splanchnic Nerve in Heart Failure With Preserved Ejection Fraction: The REBALANCE-HF Trial. J Card Fail. 2025 Feb 13 [Epub ahead of print]
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  53. Zalawadiya SK, Kiernan M, Borlaug BA, Stevenson LW, Desai AS, Bennett M, Mullens W, Hiivala NJ, Owens MM, Klein L. Changes in Seated Pulmonary Artery Pressure in Response to Titration of Heart Failure Medications During Ambulatory Monitoring. J Card Fail. 2025 Feb 11 [Epub ahead of print]
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  54. Molinsky RL, Shah A, Yuzefpolskaya M, Yu B, Misialek JR, Bohn B, Vock D, MacLehose R, Borlaug BA, Colombo PC, Ndumele CE, Ishigami J, Matsushita K, Lutsey PL, Demmer RT. Infection-Related Hospitalization and Incident Heart Failure: The Atherosclerosis Risk in Communities Study. J Am Heart Assoc. 2025 Feb 4; 14 (3):e033877 Epub 2025 Jan 30
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  55. Monzo L, Jarolim P, Borlaug BA, Benes J, Jurcova I, Jenca D, Kroupova K, Wohlfahrt P, Kotrc M, Melenovsky V. Growth Differentiation Factor-15 Is Associated With Congestion-Related Anorexia and Weight Loss in Advanced Heart Failure. JACC Heart Fail. 2025 Feb; 13 (2):315-329 Epub 2025 Jan 08
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  56. Egbe AC, Ali AE, Miranda WR, Connolly HM, Borlaug BA. Aerobic Capacity of Adults With Fontan Palliation: Disease-Specific Reference Values and Relationship to Outcomes. Circ Heart Fail. 2025 Feb; 18 (2):e011981 Epub 2024 Dec 09
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  57. Fayyaz AU, Eltony M, Prokop LJ, Koepp KE, Borlaug BA, Dasari S, Bois MC, Margulies KB, Maleszewski JJ, Wang Y, Redfield MM. Pathophysiological insights into HFpEF from studies of human cardiac tissue. Nat Rev Cardiol. 2025 Feb; 22 (2):90-104 Epub 2024 Aug 28
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  58. Naser JA, Harada T, Reddy YN, Pislaru SV, Michelena HI, Scott CG, Kennedy AM, Pellikka PA, Nkomo VT, Eleid MF, Borlaug BA. Prevalence of HFpEF in Isolated Severe Secondary Tricuspid Regurgitation. JAMA Cardiol 2025 Feb 1; 10 (2):182-187
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  59. Borlaug BA, Zile MR, Kramer CM, Baum SJ, Hurt K, Litwin SE, Murakami M, Ou Y, Upadhyay N, Packer M. Effects of tirzepatide on circulatory overload and end-organ damage in heart failure with preserved ejection fraction and obesity: a secondary analysis of the SUMMIT trial. Nat Med. 2025 Feb; 31 (2):544-551 Epub 2024 Nov 17
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  60. Packer M, Zile MR, Kramer CM, Baum SJ, Litwin SE, Menon V, Ge J, Weerakkody GJ, Ou Y, Bunck MC, Hurt KC, Murakami M, Borlaug BA, SUMMIT Trial Study Group. Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity. N Engl J Med. 2025 Jan 30; 392 (5):427-437 Epub 2024 Nov 16
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  61. Hortegal RA, Jain CC, Reddy YNV, Borlaug BA, Egbe AC, Miranda WR. Single-leg supine cycling: An alternative for patients requiring exercise catheterization and femoral access. Eur J Heart Fail. 2025 Jan 17 [Epub ahead of print]
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  62. Doi S, Borlaug BA. Pericardiotomy as a novel treatment for heart failure with preserved ejection fraction. Heart Fail Rev. 2025 Jan; 30 (1):137-142 Epub 2024 Oct 08
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  63. Egbe AC, Reddy YNV, Miranda WR, Jain CC, Anderson JH, Connolly HM, Borlaug BA. Clinical features, hemodynamics, and outcomes of pulmonary hypertension in adults with coarctation of aorta. Int J Cardiol. 2025 Jan 1; 418:132634 Epub 2024 Oct 11
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  64. Yaku H, Eicher JC, Bergmann MW, Kister T, Porner TC, Borlaug BA, Mohan RC, Price M, Komtebedde J, Shah SJ. Management of flow reversal in patients with atrial shunts implanted to reduce left atrial pressure. JACC: Case Reports. 2025; 30 (17):103893
  65. Fudim M, Borlaug BA, Mohan RC, Price MJ, Fail P, Goyal P, Hummel SL, Zirakashvili T, Shaburishvili T, Patel RB, Reddy VY, Nielsen CD, Chetcuti SJ, Sukul D, Gulati R, Kim L, Benzuly K, Mitter SS, Klein L, Uriel N, Augostini RS, Blair JE, Rocha-Singh K, Burkhoff D, Patel MR, Somo SI, Litwin SE, Shah SJ. Endovascular Ablation of the Greater Splanchnic Nerve in Heart Failure With Preserved Ejection Fraction: The REBALANCE-HF Randomized Clinical Trial. JAMA Cardiol. 2024 Dec 1; 9 (12):1143-1153
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  66. Egbe AC, Reddy YNV, Ali AE, Younis A, Borlaug BA. Clinical features, haemodynamics, and outcomes of heart failure with preserved ejection fraction in coarctation of aorta. Eur J Heart Fail. 2024 Dec; 26 (12):2595-2603 Epub 2024 July 16
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  67. Naser JA, Harada T, Tada A, Doi S, Tsaban G, Pislaru SV, Nkomo VT, Scott CG, Kennedy AM, Eleid MF, Reddy YNV, Lin G, Pellikka PA, Borlaug BA. Prevalence, Incidence, and Outcomes of Diastolic Dysfunction in Isolated Tricuspid Regurgitation: Perhaps Not Really "Isolated"? JACC Cardiovasc Imaging. 2024 Dec; 17 (12):1411-1424 Epub 2024 July 24
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  68. Hammer SM, Bruhn EJ, Bissen TG, Cifci G, Borlaug BA, Olson TP, Smith JR. Impaired Vastus Lateralis Blood Flow During Cycling Exercise in Heart Failure With Preserved Ejection Fraction. J Card Fail. 2024 Dec; 30 (12):1637-1640 Epub 2024 May 20
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  69. Litwin SE, Komtebedde J, Borlaug BA, Kaye DM, Hasenfubeta G, Kawash R, Hoendermis E, Hummel SL, Cikes M, Gustafsson F, Chung ES, Mohan RC, Sverdlov AL, Swarup V, Winkler S, Hayward CS, Bergmann MW, Bugger H, McKenzie S, Nair A, Rieth A, Burkhoff D, Cutlip DE, Solomon SD, van Veldhuisen DJ, Leon MB, Shah SJ. Long term safety and outcomes after atrial shunting for heart failure with preserved or mildly reduced ejection fraction: 5-year and 3-year follow-up in the REDUCE LAP-HF I and II trials. Am Heart J. 2024 Dec; 278:106-116 Epub 2024 Sept 03
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  70. Jain CC, Egbe AC, Allison TG, van de Bruaene A, Borlaug BA, Connolly HM, Burchill LJ, Miranda WR. Functional Capacity Assessment in Adults After Fontan Palliation: A Cardiopulmonary Exercise Test-Invasive Exercise Hemodynamics Correlation Study. Am J Cardiol. 2024 Dec 1; 232:82-88 Epub 2024 Sept 06
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  71. Akhiyat N, Anand V, Kumar V, Ryu A, Gibbons R, Borlaug BA, Chandrasekaran K, Abou Ezzeddine O, Anavekar N. The myocardial function index (MFI): An integrated measure of cardiac function in AL-cardiomyopathy. Int J Cardiol Heart Vasc. 2024 Dec; 55:101525 Epub 2024 Oct 15
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  72. Reddy YNV, Frantz RP, Hassoun PM, Hemnes AR, Horn E, Leopold JA, Rischard F, Rosenzweig EB, Hill NS, Erzurum SC, Beck GJ, Finet JE, Jellis CL, Mathai SC, Tang WHW, Borlaug BA. Clinical Implications of Pretest Probability of HFpEF on Outcomes in Precapillary Pulmonary Hypertension. J Am Coll Cardiol. 2024 Nov 26; 84 (22):2196-2210 Epub 2024 Oct 23
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  73. Sharif SM, Smith JR, Borlaug BA, Olson TP. Association between locomotor muscle quality and cardiac function during exercise in heart failure with preserved ejection fraction. Eur J Heart Fail. 2024 Nov 19 [Epub ahead of print]
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  74. Gopalasingam N, Berg-Hansen K, Christensen KH, Ladefoged BT, Poulsen SH, Andersen MJ, Borlaug BA, Nielsen R, Moller N, Wiggers H. Randomized Crossover Trial of 2-Week Ketone Ester Treatment in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction. Circulation. 2024 Nov 12; 150 (20):1570-1583 Epub 2024 Aug 20
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  75. Reddy YNV, Miranda WR, Jain CC, Borlaug BA, Egbe AC. Haemodynamic contributors to pulmonary hypertension across the spectrum of adult congenital heart disease. Eur J Heart Fail. 2024 Nov; 26 (11):2356-2366 Epub 2024 July 02
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