Publications

  1. Ryu AJ, Kumar V, Borlaug BA, Manduca A, Rao CK, Gibbons RJ, Asirvatham SJ, Gersh BJ, Chandrasekaran K, Araoz PA, Oh JK, Egbe AC, Behfar A, Anavekar NS. Systolic-to-diastolic myocardial volume ratio as a novel imaging marker of cardiomyopathy. Int J Cardiol. 2021 Jan 1; 322:272-277 Epub 2020 Aug 12
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  2. Kumar V, Ryu AJ, Manduca A, Rao C, Gibbons RJ, Gersh BJ, Chandrasekaran K, Asirvatham SJ, Araoz PA, Oh JK, Egbe AC, Behfar A, Borlaug BA, Anavekar NS. Cardiac MRI demonstrates compressibility in healthy myocardium but not in myocardium with reduced ejection fraction. Int J Cardiol. 2021 Jan 1; 322:278-283 Epub 2020 Aug 29
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  3. Monzo L, Sedlacek K, Hromanikova K, Tomanova L, Borlaug BA, Jabor A, Kautzner J, Melenovsky V. Ketone body metabolism in failing heart. Metabolism. 2020 Nov 25; 154452 [Epub ahead of print]
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  4. Sorimachi H, Obokata M, Takahashi N, Reddy YNV, Jain CC, Verbrugge FH, Koepp KE, Khosla S, Jensen MD, Borlaug BA. Pathophysiologic importance of visceral adipose tissue in women with heart failure and preserved ejection fraction. Eur Heart J. 2020 Nov 23 [Epub ahead of print]
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  5. Monzo L, Reichenbach A, Al-Hiti H, Borlaug BA, Havlenova T, Solar N, Tupy M, Ters J, Kautzner J, Melenovsky V. ACUTE UNLOADING EFFECTS OF SILDENAFIL ENHANCE RIGHT VENTRICULAR-PULMONARY ARTERY COUPLING IN HEART FAILURE. J Card Fail. 2020 Nov 21 [Epub ahead of print]
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  6. Ng ACT, Delgado V, Borlaug BA, Bax JJ. Diabesity: the combined burden of obesity and diabetes on heart disease and the role of imaging. Nat Rev Cardiol. 2020 Nov 13 [Epub ahead of print]
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  7. Jain CC, Borlaug BA. Performance and Interpretation of Invasive Hemodynamic Exercise Testing. Chest. 2020 Nov; 158 (5):2119-2129 Epub 2020 May 28
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  8. Fermoyle CC, Stewart GM, Borlaug BA, Johnson BD. Effects of exercise on thoracic blood volumes, lung fluid accumulation, and pulmonary diffusing capacity in heart failure with preserved ejection fraction. Am J Physiol Regul Integr Comp Physiol. 2020 Nov 1; 319 (5):R602-R609 Epub 2020 Sept 16
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  9. Jentzer JC, Anavekar NS, Burstein BJ, Borlaug BA, Oh JK. Noninvasive Echocardiographic Left Ventricular Stroke Work Index Predicts Mortality in Cardiac Intensive Care Unit Patients. Circ Cardiovasc Imaging. 2020 Nov; 13 (11):e011642 Epub 2020 Nov 16
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  10. Pugliese NR, De Biase N, Conte L, Gargani L, Mazzola M, Fabiani I, Natali A, Dini FL, Frumento P, Rosada J, Taddei S, Borlaug BA, Masi S. Cardiac Reserve and Exercise Capacity: Insights from Combined Cardiopulmonary and Exercise Echocardiography Stress Testing. J Am Soc Echocardiogr. 2020 Oct 6 Epub 2020 Oct 06
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  11. Egbe AC, Connolly HM, Miranda WR, Scott CG, Borlaug BA. Prognostic implications of inferior vena cava haemodynamics in ambulatory patients with tetralogy of Fallot. ESC Heart Fail. 2020 Oct; 7 (5):2589-2596 Epub 2020 June 26
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  12. Taher R, Sara JD, Toya T, Borlaug BA, Lerman LO, Lerman A. Peripheral endothelial dysfunction is a novel risk factor for systolic dysfunction and heart failure progression. Int J Cardiol Heart Vasc. 2020 Oct; 30:100584 Epub 2020 July 23
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  13. Jain CC, Egbe AC, Borlaug BA. Every Now and Then I Fall Apart: Total Eclipse of the Mitral Valve. Circ Heart Fail. 2020 Oct; 13 (10):e007145 Epub 2020 Sept 08
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  14. Borlaug BA, Maleszewski JJ. The heavy heart of HFpEF. Eur Heart J. 2020 Sep 21; 41 (36):3447
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  15. Ahmad A, Corban MT, Toya T, Verbrugge FH, Sara JD, Lerman LO, Borlaug BA, Lerman A. Coronary microvascular dysfunction is associated with exertional haemodynamic abnormalities in patients with heart failure with preserved ejection fraction. Eur J Heart Fail. 2020 Sep 19 Epub 2020 Sept 19
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  16. Verbrugge FH, Guazzi M, Testani JM, Borlaug BA. Altered Hemodynamics and End-Organ Damage in Heart Failure: Impact on the Lung and Kidney. Circulation. 2020 Sep 8; 142 (10):998-1012 Epub 2020 Sept 08
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  17. Smith JR, Joyner MJ, Curry TB, Borlaug BA, Keller-Ross ML, Van Iterson EH, Olson TP. Locomotor muscle group III/IV afferents constrain stroke volume and contribute to exercise intolerance in human heart failure. J Physiol. 2020 Sep 4 Epub 2020 Sept 04
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  18. Del Buono MG, Iannaccone G, Scacciavillani R, Carbone S, Camilli M, Niccoli G, Borlaug BA, Lavie CJ, Arena R, Crea F, Abbate A. Heart failure with preserved ejection fraction diagnosis and treatment: An updated review of the evidence. Prog Cardiovasc Dis. 2020 Sep - Oct; 63 (5):570-584 Epub 2020 May 05
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  19. Packer M, Lam CSP, Lund LH, Maurer MS, Borlaug BA. Characterization of the inflammatory-metabolic phenotype of heart failure with a preserved ejection fraction: a hypothesis to explain influence of sex on the evolution and potential treatment of the disease. Eur J Heart Fail. 2020 Sep; 22 (9):1551-1567 Epub 2020 June 26
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  20. Stewart GM, Johnson BD, Sprecher DL, Reddy YNV, Obokata M, Goldsmith S, Bart B, Oughton A, Fillmore C, Behm DJ, Borlaug BA. Targeting pulmonary capillary permeability to reduce lung congestion in heart failure: a randomized, controlled pilot trial. Eur J Heart Fail. 2020 Sep; 22 (9):1641-1645 Epub 2020 Mar 30
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  21. Borlaug BA. Evaluation and management of heart failure with preserved ejection fraction. Nat Rev Cardiol. 2020 Sep; 17 (9):559-573 Epub 2020 Mar 30
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  22. Griffin JM, Borlaug BA, Komtebedde J, Litwin SE, Shah SJ, Kaye DM, Hoendermis E, Hasenfuss G, Gustafsson F, Wolsk E, Uriel N, Burkhoff D. Impact of Interatrial Shunts on Invasive Hemodynamics and Exercise Tolerance in Patients With Heart Failure. J Am Heart Assoc. 2020 Sep; 9 (17):e016760 Epub 2020 Aug 15
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  23. Reddy YNV, Obokata M, Verbrugge FH, Lin G, Borlaug BA. Atrial Dysfunction in Patients With Heart Failure With Preserved Ejection Fraction and Atrial Fibrillation. J Am Coll Cardiol. 2020 Sep 1; 76 (9):1051-1064
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  24. Reddy YNV, Obokata M, Jones AD, Lewis GD, Shah SJ, Abouezzedine OF, Fudim M, Alhanti B, Stevenson LW, Redfield MM, Borlaug BA. Characterization of the Progression From Ambulatory to Hospitalized Heart Failure With Preserved Ejection Fraction. J Card Fail. 2020 Aug 19 [Epub ahead of print]
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  25. D'Alto M, Badesch D, Bossone E, Borlaug BA, Brittain E, Humbert M, Naeije R. A Fluid Challenge Test for the Diagnosis of Occult Heart Failure. Chest. 2020 Aug 14 [Epub ahead of print]
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  26. Selvaraj S, Myhre PL, Vaduganathan M, Claggett BL, Matsushita K, Kitzman DW, Borlaug BA, Shah AM, Solomon SD. Application of Diagnostic Algorithms for Heart Failure With Preserved Ejection Fraction to the Community. JACC Heart Fail. 2020 Aug; 8 (8):640-653 Epub 2020 June 10
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  27. Ezzeddine FM, Mulpuru SK, Borlaug BA. A Tough Time Running Around the Block. Circ Heart Fail. 2020 Aug; 13 (8):e007182 Epub 2020 July 15
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  28. Sabbah MS, Fayyaz AU, de Denus S, Felker GM, Borlaug BA, Dasari S, Carter RE, Redfield MM. Obese-Inflammatory Phenotypes in Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2020 Aug; 13 (8):e006414 Epub 2020 July 29
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  29. Koepp KE, Obokata M, Reddy YNV, Olson TP, Borlaug BA. Hemodynamic and Functional Impact of Epicardial Adipose Tissue in Heart Failure With Preserved Ejection Fraction. JACC Heart Fail. 2020 Aug; 8 (8):657-666 Epub 2020 July 08
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  30. Fermoyle CC, Stewart GM, Borlaug BA, Johnson BD. Pulmonary Vascular Pressures and Gas Exchange Response to Exercise in Heart Failure With Preserved Ejection Fraction. J Card Fail. 2020 Aug 1 Epub 2020 Aug 01
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  31. Guazzi M, Generati G, Borlaug B, Alfonzetti E, Sugimoto T, Castelvecchio S, Menicanti L, Bandera F. Redistribution of cardiac output during exercise by functional mitral regurgitation in heart failure: compensatory O2 peripheral uptake to delivery failure. Am J Physiol Heart Circ Physiol. 2020 Jul 1; 319 (1):H100-H108 Epub 2020 May 22
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  32. Reddy YNV, Rikhi A, Obokata M, Shah SJ, Lewis GD, AbouEzzedine OF, Dunlay S, McNulty S, Chakraborty H, Stevenson LW, Redfield MM, Borlaug BA. Quality of life in heart failure with preserved ejection fraction: importance of obesity, functional capacity, and physical inactivity. Eur J Heart Fail. 2020 Jun; 22 (6):1009-1018 Epub 2020 Mar 09
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  33. Reddy YNV, Borlaug BA, O'Connor CM, Gersh BJ. Novel approaches to the management of chronic systolic heart failure: future directions and unanswered questions. Eur Heart J. 2020 May 7; 41 (18):1764-1774
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  34. Egbe AC, Pellikka PA, Miranda WR, Bonnichsen C, Reddy YNV, Borlaug BA, Connolly HM. Echocardiographic predictors of severe right ventricular diastolic dysfunction in tetralogy of Fallot: Relations to patient outcomes. Int J Cardiol. 2020 May 1; 306:49-55 Epub 2020 Feb 27
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  35. Redouane B, Greene SJ, Fudim M, Vaduganathan M, Ambrosy AP, Sun JL, DeVore AD, McNulty SE, Mentz RJ, Hernandez AF, Felker GM, Cooper LB, Borlaug BA, Velazquez EJ, Margulies KB, Sharma A. Effects of Liraglutide on Worsening Renal Function Among Patients With Heart Failure With Reduced Ejection Fraction: Insights From the FIGHT Trial. Circ Heart Fail. 2020 May; 13 (5):e006758 Epub 2020 May 04
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  36. Guglin M, Zucker MJ, Borlaug BA, Breen E, Cleveland J, Johnson MR, Panjrath GS, Patel JK, Starling RC, Bozkurt B, ACC Heart Failure and Transplant Member Section and Leadership Council. Evaluation for Heart Transplantation and LVAD Implantation: JACC Council Perspectives. J Am Coll Cardiol. 2020 Mar 31; 75 (12):1471-1487
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  37. Shah SJ, Borlaug BA, Kitzman DW, McCulloch AD, Blaxall BC, Agarwal R, Chirinos JA, Collins S, Deo RC, Gladwin MT, Granzier H, Hummel SL, Kass DA, Redfield MM, Sam F, Wang TJ, Desvigne-Nickens P, Adhikari BB. Research Priorities for Heart Failure With Preserved Ejection Fraction: National Heart, Lung, and Blood Institute Working Group Summary. Circulation. 2020 Mar 24; 141 (12):1001-1026 Epub 2020 Mar 23
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  38. Tamargo M, Obokata M, Reddy YNV, Pislaru SV, Lin G, Egbe AC, Nishimura RA, Borlaug BA. Functional mitral regurgitation and left atrial myopathy in heart failure with preserved ejection fraction. Eur J Heart Fail. 2020 Mar; 22 (3):489-498 Epub 2020 Jan 07
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  39. Patel RB, Mehta R, Redfield MM, Borlaug BA, Hernandez AF, Shah SJ, Dubin RF. Renal Dysfunction in Heart Failure With Preserved Ejection Fraction: Insights From the RELAX Trial. J Card Fail. 2020 Mar; 26 (3):233-242 Epub 2020 Jan 11
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  40. Yang JH, Obokata M, Reddy YNV, Redfield MM, Lerman A, Borlaug BA. Endothelium-dependent and independent coronary microvascular dysfunction in patients with heart failure with preserved ejection fraction. Eur J Heart Fail. 2020 Mar; 22 (3):432-441 Epub 2019 Dec 15
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  41. Miranda WR, Hagler DJ, Taggart NW, Borlaug BA, Connolly HM, Egbe AC. Elevated ventricular filling pressures and long-term survival in adults post-Fontan. Catheter Cardiovasc Interv. 2020 Mar 1; 95 (4):803-809 Epub 2019 May 30
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  42. Tang WHW, Wilcox JD, Jacob MS, Rosenzweig EB, Borlaug BA, Frantz RP, Hassoun PM, Hemnes AR, Hill NS, Horn EM, Singh HS, Systrom DM, Tedford RJ, Vanderpool RR, Waxman AB, Xiao L, Leopold JA, Rischard FP. Comprehensive Diagnostic Evaluation of Cardiovascular Physiology in Patients With Pulmonary Vascular Disease: Insights From the PVDOMICS Program. Circ Heart Fail. 2020 Mar; 13 (3):e006363 Epub 2020 Feb 24
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  43. Egbe AC, Vojjini R, Badawy M, Jain V, Bonnichsen CR, Reddy YNV, Obokata M, Borlaug BA. Heightened Dependence of Left-Heart Filling Pressures on Right-Heart Failure in Congenital Heart Disease. Can J Cardiol. 2020 Feb 26 [Epub ahead of print]
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  44. Jain CC, Borlaug BA. Hemodynamic assessment in heart failure. Catheter Cardiovasc Interv. 2020 Feb 15; 95 (3):420-428 Epub 2019 Sept 10
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  45. Miller WL, Borlaug BA. Impact of Obesity on Volume Status in Patients With Ambulatory Chronic Heart Failure. J Card Fail. 2020 Feb; 26 (2):112-117 Epub 2019 Sept 27
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  46. Reddy YNV, Obokata M, Testani JM, Felker GM, Tang WHW, Abou-Ezzeddine OF, Sun JL, Chakrabothy H, McNulty S, Shah SJ, Lewis GD, Stevenson LW, Redfield MM, Borlaug BA. Adverse Renal Response to Decongestion in the Obese Phenotype of Heart Failure With Preserved Ejection Fraction. J Card Fail. 2020 Feb; 26 (2):101-107 Epub 2019 Oct 13
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  47. Obokata M, Kane GC, Sorimachi H, Reddy YNV, Olson TP, Egbe AC, Melenovsky V, Borlaug BA. Noninvasive evaluation of pulmonary artery pressure during exercise: the importance of right atrial hypertension. Eur Respir J. 2020 Feb; 55 (2) Epub 2020 Feb 12
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  48. Egbe AC, Reddy YNV, Obokata M, Borlaug BA. Doppler-Derived Arterial Load Indices Better Reflect Left Ventricular Afterload Than Systolic Blood Pressure in Coarctation of Aorta. Circ Cardiovasc Imaging. 2020 Feb; 13 (2):e009672 Epub 2020 Feb 13
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  49. Obokata M, Reddy YNV, Borlaug BA. Diastolic Dysfunction and Heart Failure With Preserved Ejection Fraction: Understanding Mechanisms by Using Noninvasive Methods. JACC Cardiovasc Imaging. 2020 Jan; 13 (1 Pt 2):245-257 Epub 2019 June 12
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  50. Sara JDS, Maor E, Borlaug B, Lewis BR, Orbelo D, Lerman LO, Lerman A. Non-invasive vocal biomarker is associated with pulmonary hypertension. PLoS One. 2020; 15 (4):e0231441 Epub 2020 Apr 16
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  51. Hanff TC, Kaye DM, Hayward CS, Post MC, Malek F, Hasenfubeta G, Gustafsson F, Burkhoff D, Shah SJ, Litwin SE, Kahwash R, Hummel SL, Borlaug BA, Solomon SD, Lam CSP, Komtebedde J, Silvestry FE, REDUCE LAP-HF study investigators, and research staff. Assessment of Predictors of Left Atrial Volume Response to a Transcatheter InterAtrial Shunt Device (from the REDUCE LAP-HF Trial). Am J Cardiol. 2019 Dec 15; 124 (12):1912-1917 Epub 2019 Sept 26
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  52. Egbe AC, Taggart NW, Reddy YNV, Sufian M, Banala K, Vojjini R, Najam M, Osman K, Obokata M, Borlaug BA. Assessment and Implications of Right Ventricular Afterload in Tetralogy of Fallot. Am J Cardiol. 2019 Dec 1; 124 (11):1780-1784 Epub 2019 Sept 09
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  53. Obokata M, Kane GC, Reddy YNV, Melenovsky V, Olson TP, Jarolim P, Borlaug BA. The neurohormonal basis of pulmonary hypertension in heart failure with preserved ejection fraction. Eur Heart J. 2019 Dec 1; 40 (45):3707-3717
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  54. Reddy YNV, Obokata M, Wiley B, Koepp KE, Jorgenson CC, Egbe A, Melenovsky V, Carter RE, Borlaug BA. The haemodynamic basis of lung congestion during exercise in heart failure with preserved ejection fraction. Eur Heart J. 2019 Dec 1; 40 (45):3721-3730
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  55. Obokata M, Reddy YNV, Shah SJ, Kaye DM, Gustafsson F, Hasenfubeta G, Hoendermis E, Litwin SE, Komtebedde J, Lam C, Burkhoff D, Borlaug BA. Effects of Interatrial Shunt on Pulmonary Vascular Function in Heart Failure With Preserved Ejection Fraction. J Am Coll Cardiol. 2019 Nov 26; 74 (21):2539-2550
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  56. Egbe AC, Bonnichsen C, Reddy YNV, Anderson JH, Borlaug BA. Pathophysiologic and Prognostic Implications of Right Atrial Hypertension in Adults With Tetralogy of Fallot. J Am Heart Assoc. 2019 Nov 19; 8 (22):e014148 Epub 2019 Nov 08
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  57. Eleid MF, Padang R, Pislaru SV, Greason KL, Crestanello J, Nkomo VT, Pellikka PA, Jentzer JC, Gulati R, Sandhu GS, Holmes DR Jr, Nishimura RA, Rihal CS, Borlaug BA. Effect of Transcatheter Aortic Valve Replacement on Right Ventricular-Pulmonary Artery Coupling. JACC Cardiovasc Interv. 2019 Nov 11; 12 (21):2145-2154
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  58. AbouEzzeddine OF, Kemp BJ, Borlaug BA, Mullan BP, Behfar A, Pislaru SV, Fudim M, Redfield MM, Chareonthaitawee P. Myocardial Energetics in Heart Failure With Preserved Ejection Fraction. Circ Heart Fail. 2019 Oct; 12 (10):e006240 Epub 2019 Oct 15
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  59. Egbe AC, Kothapalli S, Borlaug BA, Ammash NM, Najam M, Bajwa N, Tarek K, Mathew J, Connolly HM. Mechanism and Risk Factors for Death in Adults With Tetralogy of Fallot. Am J Cardiol. 2019 Sep 1; 124 (5):803-807 Epub 2019 June 07
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  60. Reddy YNV, Anantha-Narayanan M, Obokata M, Koepp KE, Erwin P, Carter RE, Borlaug BA. Hemodynamic Effects of Weight Loss in Obesity: A Systematic Review and Meta-Analysis. JACC Heart Fail. 2019 Aug; 7 (8):678-687 Epub 2019 July 10
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  61. Yang JH, Miranda WR, Borlaug BA, Nishimura RA, Schaff HV, Greason KL, Maleszewski JJ, Oh JK. Right Atrial/Pulmonary Arterial Wedge Pressure Ratio in Primary and Mixed Constrictive Pericarditis. J Am Coll Cardiol. 2019 Jul 2; 73 (25):3312-3321
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  62. Reddy YNV, Lewis GD, Shah SJ, Obokata M, Abou-Ezzedine OF, Fudim M, Sun JL, Chakraborty H, McNulty S, LeWinter MM, Mann DL, Stevenson LW, Redfield MM, Borlaug BA. Characterization of the Obese Phenotype of Heart Failure With Preserved Ejection Fraction: A RELAX Trial Ancillary Study. Mayo Clin Proc. 2019 Jul; 94 (7):1199-1209
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  63. Egbe AC, Kothapalli S, Miranda WR, Pislaru S, Ammash NM, Borlaug BA, Pellikka PA, Najam M, Connolly HM. Assessment of Right Ventricular-Pulmonary Arterial Coupling in Chronic Pulmonary Regurgitation. Can J Cardiol. 2019 Jul; 35 (7):914-922 Epub 2019 Mar 18
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  64. Borlaug BA, Reddy YNV. The Role of the Pericardium in Heart Failure: Implications for Pathophysiology and Treatment. JACC Heart Fail. 2019 Jul; 7 (7):574-585
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  65. Reddy YNV, Obokata M, Egbe A, Yang JH, Pislaru S, Lin G, Carter R, Borlaug BA. Left atrial strain and compliance in the diagnostic evaluation of heart failure with preserved ejection fraction. Eur J Heart Fail. 2019 Jul; 21 (7):891-900 Epub 2019 Mar 28
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  66. Egbe AC, Miranda WR, Pellikka PA, Pislaru SV, Borlaug BA, Kothapalli S, Ananthaneni S, Sandhyavenu H, Najam M, Farouk Abdelsamid M, Connolly HM. Right ventricular and pulmonary vascular function indices for risk stratification of patients with pulmonary regurgitation. Congenit Heart Dis. 2019 Jul; 14 (4):657-664 Epub 2019 Apr 08
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  67. Miranda WR, Borlaug BA, Hagler DJ, Connolly HM, Egbe AC. Haemodynamic profiles in adult Fontan patients: associated haemodynamics and prognosis. Eur J Heart Fail. 2019 Jun; 21 (6):803-809 Epub 2019 Jan 23
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  68. Nishimura RA, Borlaug BA. Diastology for the clinician. J Cardiol. 2019 Jun; 73 (6):445-452 Epub 2019 Mar 25
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  69. Pfeffer MA, Shah AM, Borlaug BA. Heart Failure With Preserved Ejection Fraction In Perspective. Circ Res. 2019 May 24; 124 (11):1598-1617
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  70. Del Buono MG, Arena R, Borlaug BA, Carbone S, Canada JM, Kirkman DL, Garten R, Rodriguez-Miguelez P, Guazzi M, Lavie CJ, Abbate A. Exercise Intolerance in Patients With Heart Failure: JACC State-of-the-Art Review. J Am Coll Cardiol. 2019 May 7; 73 (17):2209-2225
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  71. Smith JR, Borlaug BA, Olson TP. Exercise Ventilatory Efficiency in Older and Younger Heart Failure Patients With Preserved Ejection Fraction. J Card Fail. 2019 Apr; 25 (4):278-285 Epub 2019 Feb 27
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  72. Obokata M, Reddy YNV, Borlaug BA. The Role of Echocardiography in Heart Failure with Preserved Ejection Fraction: What Do We Want from Imaging? Heart Fail Clin. 2019 Apr; 15 (2):241-256 Epub 2019 Feb 02
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  73. Wolsk E, Kaye D, Komtebedde J, Shah SJ, Borlaug BA, Burkhoff D, Kitzman DW, Lam CSP, van Veldhuisen DJ, Ponikowski P, Petrie MC, Hassager C, Moller JE, Gustafsson F. Central and Peripheral Determinants of Exercise Capacity in Heart Failure Patients With Preserved Ejection Fraction. JACC Heart Fail. 2019 Apr; 7 (4):321-332 Epub 2019 Mar 06
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  74. El Sabbagh A, Reddy YNV, Barros-Gomes S, Borlaug BA, Miranda WR, Pislaru SV, Nishimura RA, Pellikka PA. Low-Gradient Severe Mitral Stenosis: Hemodynamic Profiles, Clinical Characteristics, and Outcomes. J Am Heart Assoc. 2019 Mar 5; 8 (5):e010736
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  75. Obokata M, Reddy YNV, Melenovsky V, Pislaru S, Borlaug BA. Deterioration in right ventricular structure and function over time in patients with heart failure and preserved ejection fraction. Eur Heart J. 2019 Feb 21; 40 (8):689-697
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  76. Reddy YNV, Obokata M, Koepp KE, Egbe AC, Wiley B, Borlaug BA. The beta-Adrenergic Agonist Albuterol Improves Pulmonary Vascular Reserve in Heart Failure With Preserved Ejection Fraction. Circ Res. 2019 Jan 18; 124 (2):306-314
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  77. Smith JR, Van Iterson EH, Johnson BD, Borlaug BA, Olson TP. Exercise ventilatory inefficiency in heart failure and chronic obstructive pulmonary disease. Int J Cardiol. 2019 Jan 1; 274:232-236 Epub 2018 Sept 05
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  78. Chignalia AZ, Isbatan A, Patel M, Ripper R, Sharlin J, Shosfy J, Borlaug BA, Dull RO. Pressure-dependent NOS activation contributes to endothelial hyperpermeability in a model of acute heart failure. Biosci Rep. 2018 Dec 21; 38 (6) Epub 2018 Nov 23
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  79. Fudim M, Ambrosy AP, Sun JL, Anstrom KJ, Bart BA, Butler J, AbouEzzeddine O, Greene SJ, Mentz RJ, Redfield MM, Reddy YNV, Vaduganathan M, Braunwald E, Hernandez AF, Borlaug BA, Felker GM. High-Sensitivity Troponin I in Hospitalized and Ambulatory Patients With Heart Failure With Preserved Ejection Fraction: Insights From the Heart Failure Clinical Research Network. J Am Heart Assoc. 2018 Dec 18; 7 (24):e010364
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  80. Sharma A, Ambrosy AP, DeVore AD, Margulies KB, McNulty SE, Mentz RJ, Hernandez AF, Michael Felker G, Cooper LB, Lala A, Vader J, Groake JD, Borlaug BA, Velazquez EJ. Liraglutide and weight loss among patients with advanced heart failure and a reduced ejection fraction: insights from the FIGHT trial. ESC Heart Fail. 2018 Dec; 5 (6):1035-1043 Epub 2018 Aug 17
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  81. Egbe AC, Miranda WR, Said SM, Pislaru SV, Pellikka PA, Borlaug BA, Kothapalli S, Connolly HM. Risk stratification and clinical outcomes after surgical pulmonary valve replacement. Am Heart J. 2018 Dec; 206:105-112 Epub 2018 Sept 29
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  82. Egbe AC, Reddy YNV, Khan AR, Al-Otaibi M, Akintoye E, Obokata M, Borlaug BA. Venous congestion and pulmonary vascular function in Fontan circulation: Implications for prognosis and treatment. Int J Cardiol. 2018 Nov 15; 271:312-316
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  83. Borlaug BA, Schaff HV, Pochettino A, Pedrotty DM, Asirvatham SJ, Abel MD, Carter RE, Mauermann WJ. Pericardiotomy Enhances Left Ventricular Diastolic Reserve With Volume Loading in Humans. Circulation 2018 Nov 13; 138 (20):2295-2297
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  84. Borlaug BA, Anstrom KJ, Lewis GD, Shah SJ, Levine JA, Koepp GA, Givertz MM, Felker GM, LeWinter MM, Mann DL, Margulies KB, Smith AL, Tang WHW, Whellan DJ, Chen HH, Davila-Roman VG, McNulty S, Desvigne-Nickens P, Hernandez AF, Braunwald E, Redfield MM, National Heart, Lung, and Blood Institute Heart Failure Clinical Research Network. Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction: The INDIE-HFpEF Randomized Clinical Trial. JAMA. 2018 Nov 6; 320 (17):1764-1773
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  85. Melenovsky V, Hlavata K, Sedivy P, Dezortova M, Borlaug BA, Petrak J, Kautzner J, Hajek M. Skeletal Muscle Abnormalities and Iron Deficiency in Chronic Heart FailureAn Exercise (31)P Magnetic Resonance Spectroscopy Study of Calf Muscle. Circ Heart Fail. 2018 Sep; 11 (9):e004800
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  86. Obokata M, Reddy YNV, Yang JH, Wiley BM, Borlaug BA. Left Atrial Contracture or Failure to Dilate. Circ Heart Fail. 2018 Sep; 11 (9):e005163
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  87. Reddy YNV, Carter RE, Obokata M, Redfield MM, Borlaug BA. A Simple, Evidence-Based Approach to Help Guide Diagnosis of Heart Failure With Preserved Ejection Fraction. Circulation. 2018 Aug 28; 138 (9):861-870
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  88. Gorter TM, Obokata M, Reddy YNV, Melenovsky V, Borlaug BA. Exercise unmasks distinct pathophysiologic features in heart failure with preserved ejection fraction and pulmonary vascular disease. Eur Heart J. 2018 Aug 7; 39 (30):2825-2835
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  89. Obokata M, Olson TP, Reddy YNV, Melenovsky V, Kane GC, Borlaug BA. Haemodynamics, dyspnoea, and pulmonary reserve in heart failure with preserved ejection fraction. Eur Heart J. 2018 Aug 7; 39 (30):2810-2821
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  90. Parikh KS, Sharma K, Fiuzat M, Surks HK, George JT, Honarpour N, Depre C, Desvigne-Nickens P, Nkulikiyinka R, Lewis GD, Gomberg-Maitland M, O'Connor CM, Stockbridge N, Califf RM, Konstam MA, Januzzi JL Jr, Solomon SD, Borlaug BA, Shah SJ, Redfield MM, Felker GM. Heart Failure With Preserved Ejection Fraction Expert Panel Report: Current Controversies and Implications for Clinical Trials. JACC Heart Fail. 2018 Aug; 6 (8):619-632
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  91. Reddy YNV, Olson TP, Obokata M, Melenovsky V, Borlaug BA. Hemodynamic Correlates and Diagnostic Role of Cardiopulmonary Exercise Testing in Heart Failure With Preserved Ejection Fraction. JACC Heart Fail. 2018 Aug; 6 (8):665-675 Epub 2018 May 23
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  92. Fernandes-Silva MM, Shah AM, Claggett B, Cheng S, Tanaka H, Silvestre OM, Nadruz W, Borlaug BA, Solomon SD. Adiposity, body composition and ventricular-arterial stiffness in the elderly: the Atherosclerosis Risk in Communities Study. Eur J Heart Fail. 2018 Aug; 20 (8):1191-1201 Epub 2018 Apr 16
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  188. Lam CS, Shah AM, Borlaug BA, Cheng S, Verma A, Izzo J, Oparil S, Aurigemma GP, Thomas JD, Pitt B, Zile MR, Solomon SD. Effect of antihypertensive therapy on ventricular-arterial mechanics, coupling, and efficiency. Eur Heart J. 2013 Mar; 34(9):676-83. Epub 2012 Sep 10.
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  191. Borlaug BA. Invasive hemodynamic characterization of Heart Failure with preserved Ejection Fraction. Heart Failure Clinics. 2013 in press.
  192. Borlaug BA. Heart Failure with preserved EF: curret understandings and challenges. Curr Cardiol Rep. 2013 in press.
  193. Fujimoto N, Borlaug BA, Lewis GD, Hastings JL, Shafer KM, Bhella PS, Carrick-Ranson G, Levine BD. Hemodynamic responses to rapid saline loading: the impact of age, sex, and heart failure. Circulation. 2013 Jan 1; 127(1):55-62. Epub 2012 Nov 21.
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  194. Bishu K, Deswal A, Chen HH, LeWinter MM, Lewis GD, Semigran MJ, Borlaug BA, McNulty S, Hernandez AF, Braunwald E, Redfield MM. Biomarkers in acutely decompensated heart failure with preserved or reduced ejection fraction. Am Heart J. 2012 Nov; 164 (5):763-770.e3 Epub 2012 Oct 16
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  195. Mohammed SF, Borlaug BA, Roger VL, Mirzoyev SA, Rodeheffer RJ, Chirinos JA, Redfield MM. Comorbidity and ventricular and vascular structure and function in heart failure with preserved ejection fraction: a community-based study. Circ Heart Fail. 2012 Nov; 5 (6):710-9 Epub 2012 Oct 17
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  197. Fang JC, DeMarco T, Givertz MM, Borlaug BA, Lewis GD, Rame JE, Gomberg-Maitland M, Murali S, Frantz RP, McGlothlin D, Horn EM, Benza RL. World Health Organization Pulmonary Hypertension group 2: pulmonary hypertension due to left heart disease in the adult--a summary statement from the Pulmonary Hypertension Council of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2012 Sep; 31(9):913-33.
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  198. Munger TM, Dong YX, Masaki M, Oh JK, Mankad SV, Borlaug BA, Asirvatham SJ, Shen WK, Lee HC, Bielinski SJ, Hodge DO, Herges RM, Buescher TL, Wu JH, Ma C, Zhang Y, Chen PS, Packer DL, Cha YM. Electrophysiological and hemodynamic characteristics associated with obesity in patients with atrial fibrillation. J Am Coll Cardiol. 2012 Aug 28; 60(9):851-60. Epub 2012 Jun 20.
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  199. Guazzi M, Borlaug BA. Pulmonary hypertension due to left heart disease. Circulation. 2012 Aug 21; 126(8):975-90.
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  200. Andersen MJ, Ersboll M, Bro-Jeppesen J, Gustafsson F, Hassager C, Kober L, Borlaug BA, Boesgaard S, Kjaergaard J, Moller JE. Exercise hemodynamics in patients with and without diastolic dysfunction and preserved ejection fraction after myocardial infarction. Circ Heart Fail. 2012 Jul 1; 5(4):444-51. Epub 2012 Jun 15.
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  201. Schwartzenberg S, Redfield MM, From AM, Sorajja P, Nishimura RA, Borlaug BA. Effects of vasodilation in heart failure with preserved or reduced ejection fraction implications of distinct pathophysiologies on response to therapy. J Am Coll Cardiol. 2012 Jan 31; 59(5):442-51.
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  202. Tedford RJ, Hassoun PM, Mathai SC, Girgis RE, Russell SD, Thiemann DR, Cingolani OH, Mudd JO, Borlaug BA, Redfield MM, Lederer DJ, Kass DA. Pulmonary capillary wedge pressure augments right ventricular pulsatile loading. Circulation. 2012 Jan 17; 125(2):289-97. Epub 2011 Nov 30.
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  203. Gharacholou SM, Scott CG, Borlaug BA, Kane GC, McCully RB, Oh JK, Pellikka PA. Relationship between diastolic function and heart rate recovery after symptom-limited exercise. J Card Fail. 2012 Jan; 18(1):34-40. Epub 2011 Nov 09.
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  204. From AM, Lam CS, Pitta SR, Kumar PV, Balbissi KA, Booker JD, Singh IM, Sorajja P, Reeder GS, Borlaug BA. Bedside assessment of cardiac hemodynamics: the impact of noninvasive testing and examiner experience. Am J Med. 2011 Nov; 124(11):1051-7. Epub 2011 Sep 22.
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  205. Scantlebury DC, Borlaug BA. Why are women more likely than men to develop heart failure with preserved ejection fraction? Curr Opin Cardiol. 2011 Nov; 26(6):562-8.
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  209. Borlaug BA, Redfield MM. Diastolic and systolic heart failure are distinct phenotypes within the heart failure spectrum. Circulation. 2011 May 10; 123 (18):2006-13; discussion 2014
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  211. Gharacholou SM, Maleszewski JJ, Borlaug BA, Cosio FG, Dearani JA, Kushwaha SS, Ammash NM. "Carcinoid-like" tricuspid valvulopathy associated with nephrogenic systemic fibrosis. Echocardiography. 2011 Mar; 28: (3)E46-9.
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  213. Sobieszczyk P, Borlaug BA, Gornik HL, Knauft WD, Beckman JA. Glycyrrhetinic acid attenuates vascular smooth muscle vasodilatory function in healthy humans. Clin Sci (Lond). 2010 Nov; 119(10):437-42. Epub 2010 Aug 05.
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  218. Lam CS, Grewal J, Borlaug BA, Ommen SR, Kane GC, McCully RB, Pellikka PA. Size, shape, and stamina: the impact of left ventricular geometry on exercise capacity. Hypertension. 2010 May; 55 (5):1143-9 Epub 2010 Mar 09
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  219. Boilson BA, Schirger JA, Borlaug BA. Caveat medicus! Pulmonary hypertension in the elderly: a word of caution. Eur J Heart Fail. 2010 Jan; 12(1):89-93.
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  221. Madhavan M, Borlaug BA, Lerman A, Rihal CS, Prasad A. Stress hormone and circulating biomarker profile of apical ballooning syndrome (Takotsubo cardiomyopathy): insights into the clinical significance of B-type natriuretic peptide and troponin levels. Heart. 2009 Sep; 95: (17)1436-41.
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  225. Borlaug BA, Kass DA. Invasive hemodynamic assessment in heart failure. Heart Fail Clin. 2009 Apr; 5 (2):217-28
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  227. Borlaug BA. Treatment of heart failure with preserved ejection fraction. Curr Treat Options Cardiovasc Med. 2009 Feb; 11 (1):79-87
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  228. Sorajja P, Borlaug BA. Severe heart failure in the setting of relatively mild mitral stenosis: the role of invasive hemodynamic assessment. Catheter Cardiovasc Interv. 2008 Nov 1; 72(5):739-48.
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  229. Borlaug BA, Kass DA. Ventricular-vascular interaction in heart failure. Heart Fail Clin. 2008 Jan; 4 (1):23-36
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  230. Mudd JO, Borlaug BA, Johnston PV, Kral BG, Rouf R, Blumenthal RS, Kwiterovich PO Jr. Beyond low-density lipoprotein cholesterol: defining the role of low-density lipoprotein heterogeneity in coronary artery disease. J Am Coll Cardiol. 2007 Oct 30; 50(18):1735-41 Epub 2007 Oct 15.
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  231. Borlaug BA, Melenovsky V, Redfield MM, Kessler K, Chang HJ, Abraham TP, Kass DA. Impact of arterial load and loading sequence on left ventricular tissue velocities in humans. J Am Coll Cardiol. 2007 Oct 16; 50: (16)1570-7.
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  232. Melenovsky V, Borlaug BA, Fetics B, Kessler K, Shively L, Kass DA. Estimation of central pressure augmentation using automated radial artery tonometry.[see comment]. J Hypertens. 2007 Jul; 25(7):1403-9.
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  233. Lam CS, Roger VL, Rodeheffer RJ, Bursi F, Borlaug BA, Ommen SR, Kass DA, Redfield MM. Cardiac structure and ventricular-vascular function in persons with heart failure and preserved ejection fraction from Olmsted County, Minnesota. Circulation. 2007 Apr 17; 115 (15):1982-90 Epub 2007 Apr 02
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  234. Melenovsky V, Borlaug BA, Rosen B, Hay I, Ferruci L, Morell CH, Lakatta EG, Najjar SS, Kass DA. Cardiovascular features of heart failure with preserved ejection fraction versus nonfailing hypertensive left ventricular hypertrophy in the urban Baltimore community: the role of atrial remodeling/dysfunction. J Am Coll Cardiol. 2007 Jan 16; 49(2):198-207.
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  235. Borlaug BA, Melenovsky V, Russell SD, Kessler K, Pacak K, Becker LC, Kass DA. Impaired chronotropic and vasodilator reserves limit exercise capacity in patients with heart failure and a preserved ejection fraction. Circulation. 2006 Nov 14; 114(20):2138-47. Epub 2006 Nov 06.
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  236. Borlaug BA, Kass DA. Mechanisms of diastolic dysfunction in heart failure. Trends Cardiovasc Med. 2006 Nov; 16(8):273-9.
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  237. Forfia PR, Fisher MR, Mathai SC, Housten-Harris T, Hemnes AR, Borlaug BA, Chamera E, Corretti MC, Champion HC, Abraham TP, Girgis RE, Hassoun PM. Tricuspid annular displacement predicts survival in pulmonary hypertension. Am J Respir Crit Care Med. 2006 Nov 1; 174(9):1034-41. Epub 2006 Aug 03.
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  238. Borlaug BA, Melenovsky V, Marhin T, Fitzgerald P, Kass DA. Sildenafil inhibits beta-adrenergic-stimulated cardiac contractility in humans. Circulation. 2005 Oct 25; 112(17):2642-9.
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  239. Redfield MM, Jacobsen SJ, Borlaug BA, Rodeheffer RJ, Kass DA. Age- and gender-related ventricular-vascular stiffening: a community-based study. Circulation. 2005 Oct 11; 112: (15)2254-62.
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  240. Melenovsky V, Hay I, Fetics BJ, Borlaug BA, Kramer A, Pastore JM, Berger R, Kass DA. Functional impact of rate irregularity in patients with heart failure and atrial fibrillation receiving cardiac resynchronization therapy. Eur Heart J. 2005 Apr; 26(7):705-11.
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