Barry A. Boilson, M.D., has a current research interest in how to harness the capacity of the human body to heal itself in heart failure. Currently, Dr. Boilson and colleagues are studying stem cells, which are detectable in the blood, and how different treatments for heart failure, including left ventricular assist devices (LVADs), affect their longevity. Dr. Boilson is also looking at sound wave analysis as a method to detect possible problems within the LVAD pumps before they become clinically apparent.
- Circulating progenitor cells and accelerated senescence
- The impact of LVAD therapy
- Acoustic spectrograms and detection of early pump thrombosis
Significance to patient care
The ability of medical or device therapy to harness the body's capacity for cardiac healing and regeneration is not yet widely explored or understood. Understanding the mechanisms involved could allow researchers to develop new treatments focused on harnessing native stem cells. Dr. Boilson's work is increasing the understanding of how the human body and mechanical devices interact with each other, including increasing the understanding of clotting and how it affects pump function.
- Finalist, Jay N. Cohn New Investigator Award - Clinical-Integrative Physiology, Scientific Meeting of the Heart Failure Society of America, 2008