Pulmonary and Critical Care Medicine Research

Below are current clinical trials.

90 studies in Pulmonary and Critical Care Medicine Research
(all studies, either open or closed).

Filter this list of studies by location, status and more.

1. Sleep Apnea After Anterior Cervical Discectomy and Fusion

   Jacksonville, Fla.

   The purpose of this study is to determine if anterior cervical discectomy and fusion surgery result in a higher incidence of obstructive sleep apnea.

2. Phase 3 Study With Dual Release Ciprofloxacin for Inhalation in Non-CF Bronchiectasis

   Rochester, Minn.

   The DRCFI treatment will influence the time to first pulmonary exacerbation compared to placebo.

3. A Registry for United States Patients with Chronic Thromboembolic Pulmonary Hypertension

   Rochester, Minn.

   The purpose of this registry will be to promote a greater understanding of the prevalence, pathophysiology, evaluation, and treatment of United States patients with chronic thromboembolic pulmonary hypertension through shared information, education, and collaborative investigation among pulmonary hypertension centers throughout the U.S.

4. A Study of Inhaled RVT-1601 for the Treatment of Persistent Cough in Idiopathic Pulmonary Fibrosis (IPF)

   Rochester, Minn.

   The purpose of this study is to evaluate Inhaled RVT-1601 (formerly, PA101B), a new inhalation formulation of cromolyn sodium delivered via the eFlow® Closed System (CS) nebulizer, for the treatment of persistent cough in patients with idiopathic pulmonary fibrosis (IPF).

5. Study to Assess the Effectiveness and Safety of Bradanicline in Patients with Chronic Cough

   Rochester, Minn.

   The purpose of this study is to evaluate the dose-response of bradanicline in reducing awake objective cough frequency.

6. A Study to Evaluate Whether or Not Selexipag is Effective and Safe in Patients with Chronic Thromboembolic Pulmonary Hypertension when the Disease is Inoperable or Persistent/Recurrent After Surgery

   Jacksonville, Fla.

   The purpose of this study is to assess the effectiveness and safety of selexipag in subjects with inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH).

7. Reversal of Dabigatran Anticoagulant Effect With Idarucizumab

   Jacksonville, Fla.

   Evaluate the reversal of the anticoagulant effects of dabigatran by IV administration of 5.0g idarucizumab in patients treated with dabigatran etexilate who have uncontrolled bleeding or require emergency surgery or procedures.

8. A Long-Term Safety Study of JZP-110 in the Treatment of Excessive Sleepiness in Subjects With Narcolepsy or OSA

   Scottsdale/Phoenix, Ariz.

   This is a Phase 3 study to assess the long-term safety and maintenance of efficacy of JZP-110 in subjects who have completed Study 14-002, 14-003, 14-004, 15-004, 15-005, ADX-N05 201, or ADX-N05 202.

9. Study to Determine Eligibility for Lung Cancer Screening in Patients with Acute or Prior Cerebrovascular Accident (CVA)

   Jacksonville, Fla.

   The purpose of this study is to describe in detail the smoking history in a population of acute or prior cerebrovasculqar accident (CVA) patients and identify those who qualify for lung cancer screening by criteria outlined by three separate organizations.

10. LVRC IDE Crossover Study (Crossover From IDE Trial CLN0009)

    Rochester, Minn.

    The purpose of this study is to provide the lung volume reduction coil treatment procedure to patients who were randomized to the control group in study CLN0009, and obtain safety and effectiveness data on these patients.