Microscopic image of endocrine research at Mayo Clinic Leading the way to innovation

Our researchers are advancing the frontier of discovery, improving diagnosis and expanding treatment options for patients with a range of endocrine and metabolic diseases.


The Division of Endocrinology, Diabetes, Metabolism, and Nutrition-Research continually strives to improve diagnosis and treatment options for people with a wide range of endocrine and metabolic diseases.

Our endocrinologists are actively engaged in research of the endocrine and metabolic systems in laboratory and clinical research programs. Our research includes studies in prediabetes, endocrine regulation of metabolism and protein synthesis, genetic predisposition to disease, thyroid cancer, and adrenal and pituitary disorders. We also conduct clinical trials of novel and emerging therapeutics.

For patient care, Mayo Clinic's Division of Endocrinology, Diabetes, Metabolism, and Nutrition is one of the largest such practices in the world, with locations in Arizona, Florida, Minnesota and several communities throughout the Mayo Clinic Health System.

Our work builds on a long and strong history in endocrine research. In 1914, not long after joining Mayo Clinic as head of the Section of Biochemistry, Dr. Edward C. Kendall became the first scientist to purify and structurally identify thyroxine, the principal thyroid hormone. In 1950, he and another doctor received the Nobel Prize for identifying, isolating and synthesizing adrenocortical steroids — including cortisone — and introducing them as anti-inflammatory agents for the treatment of arthritis, adrenal insufficiency and other disorders.

Today, our researchers continue to advance the frontier of discovery, working closely with Mayo Clinic specialists in ophthalmology, otolaryngology, radiation oncology, surgery, obstetrics and transplantation to provide a multidisciplinary approach to address patient needs. Our research encompasses:

  • Diabetes
  • Lipids
  • Nutrition
  • Obesity
  • Osteoporosis-calcium disorders
  • Pituitary, gonad and adrenal disorders
  • Thyroid disorders
  • Transplantation