Vascular Clinical Research Training Program

measurement of segmental pressures in the lower extremity


Heit, John A., M.D.


The goal of the Mayo Clinic NIH K12 Vascular Clinical Research Training Program is to train vascular medicine, surgery and radiology specialists who will conduct translational research aimed at preventing and treating vascular diseases. The three-year training program includes one year of clinical training in the inpatient and outpatient settings, accompanied by a comprehensive multidisciplinary clinical core curriculum in vascular disease. The clinical year will include hands-on training in the vascular physiology laboratory and vascular duplex ultrasonography sufficient to qualify the graduate to sit for the RPVI and RVT credentialing examination as administered by ARDMS. In addition, the trainee will rotate through vascular angiography, endovascular therapy and CT/MRI angiography and vascular surgery as well as subspecialty clinics in early atherosclerosis, sclerotherapy, thrombophilia, vasculitis, and wound care. Opportunities for additional future cardiology or endovascular therapy training are available for successful graduates of our program. The remaining two years are completely devoted to mentored translational research training in vascular disease, including obtaining a Masters of Science degree in clinical research design and analysis, scientific presentation, and grant and scientific manuscript. The trainee will undertake a research project under the mentorship of an established NIH-funded investigator/s. In addition to presenting and publishing the project results, the goals of the mentored research years are to develop preliminary data toward the trainee's future research career program, write an entry-level NIH grant, and obtain extra mural funding and an academic appointment.

Motivation for the program

Diseases of the arteries, veins, and lymphatics are common and frequently lethal, cause chronic pain and impairment, and incur substantial costs due to health care charges and lost earnings. Few physicians are adequately trained to care for patients with vascular diseases and even fewer perform translational research in vascular disease, largely because multidisciplinary research training in vascular medicine is scarce.


To provide comprehensive training in both clinical vascular medicine as well as patient-oriented research, we have created a multidisciplinary curriculum in clinical vascular medicine, vascular biology and translational research, including a research mentorship with an established investigator. The proposed program will leverage several resources already available at the Mayo Clinic: (1) an internationally recognized multidisciplinary Vascular Center that provides care for a large number of patients with arterial, venous, and lymphatic diseases; (2) two NIH-funded (K30 and K12) clinical research training programs; and (3) over 30 investigator/mentors engaged in research relevant to vascular medicine. We have developed a multidisciplinary clinical training program in the diagnosis and care of the patient with arterial, venous or lymphatic diseases. Additional resources include comprehensive teaching tools on the principles of epidemiology (including genetic epidemiology) and biostatistics, health care economics, vascular biology, and the prevention, diagnosis and treatment of arterial, venous and lymphatic diseases. A teaching and mentoring program in the design, conduct and analysis of clinical translational research will be available to trainees.


In each year, the trainee will be eligible for educational debt relief via the NIH Loan Repayment Program ( for up to $35,000 per year in tax-free educational debt repayment. Two trainee positions per year and beginning in July are available. To be eligible, applicants must be physicians with an M.D. or D.O. degree who have completed residency training in internal medicine, surgery or radiology. Eligible applicants also must be citizens or non-citizen nationals of the United States of America or lawfully admitted to the United States of America for permanent residence. The applications must be accompanied by three letters of recommendation and a written personal statement defining the trainee's career goals.



Gonda Vascular Center
Vascular Medicine Research Faculty


The applicant must have received, as of beginning training on this grant, a Ph.D., M.D., or comparable doctoral degree. Applicant must also be a citizen or non-citizen national of the United States or must have been legally admitted as a permanent resident.