The faculty and staff of the Division of Biomedical Statistics and Informatics collaborate in and across specialized research sections.
Section of Cancer Center Statistics
The Section of Cancer Center Statistics provides statistical collaboration for research generated by Mayo Clinic Comprehensive Cancer Center investigators. Statisticians contribute to the development and execution of cancer clinical trials and other peer-reviewed clinical, translational research — for example, immunohistochemistry and the use of single or small gene sets as prognostic markers — and to educational research.
The specialization of statisticians into specific disease-oriented groups — for example, a gastrointestinal disease-oriented group and a breast cancer disease-oriented group — has been fundamental to the section's success and promotes close collaboration.
Methodological expertise in the Section of Cancer Center Statistics includes:
- Survival analysis
- All phases of clinical trial design, including innovative approaches to phase I design
- Biomarker-based clinical trials
- Assessment and validation of surrogate endpoints in oncology
- Assessment of patient reported outcomes
Section of Clinical Statistics
The Section of Clinical Statistics collaborates with researchers across Mayo Clinic on more than 2,000 ongoing institutionally and nationally funded investigations. It provides core statistical support and collaboration for major research centers and NIH-funded research programs at Mayo Clinic, including:
Methodological research in the Section of Clinical Statistics is motivated by real-world statistical challenges. These cases have led to prominent research in areas including:
- Advanced survival analysis methodology
- Categorical data analysis
- Clinical trials
- Risk modeling
The Section of Clinical Statistics has a rich continuing education program to help members of the faculty and staff stay abreast of evolving and emerging methodology and software. These activities complement the broader educational activities of the Division of Biomedical Informatics and Statistics.
Section of Computational Genomics
The Section of Computational Genomics provides study design, analytical and interpretative support to researchers engaged in research involving:
Additionally, the section maintains state-of-the-art expertise in the methods relevant to extract information and knowledge from omics data derived from family studies, case-control studies, cohort studies and prognostic studies. Its expertise covers:
- Epigenome data
- Exome data
- Transcriptome data
- Whole-genome sequencing data
The Section of Computational Genomics collaborates with researchers throughout Mayo Clinic and supports Mayo programs and centers such as the Center for Individualized Medicine (CIM) and Mayo Clinic Cancer Center.
Section of Medical Informatics
The Section of Medical Informatics conducts and facilitates team science in informatics, data science, and artificial intelligence to improve human health. Its faculty and allied health staff analyze data at all levels, from genomic to population level, to improve clinical practice, enhance knowledge management, and enable clinical and translational research.
Informatics works by collecting and organizing information, using that information to develop and test hypotheses, validating those hypotheses against real-world health problems, and incorporating the outcomes of those tests back into the knowledge base. The Section of Medical Informatics draws upon theory, methods and tools from:
- Computer science
- Information science
- Cognitive science
- Data science
- Social science
- Natural language processing
Mayo Clinic's Section of Medical Informatics is nationally and internationally recognized for its leadership in biomedical informatics and standards communities.