Funding

Studies in the Mayo Clinic Division of Emergency Medicine Research are funded by grants from the National Institutes of Health, the University of Minnesota, the American Cancer Society and other institutions.

Investigator & Role	Grant Title	Funding Source	Duration
Edward R. Melnick, M.D., M.H.S., principal investigator; Molly M. Jeffery, Ph.D., site principal investigator	EMBED: Pragmatic Trial of User-Centered Clinical Decision Support to Implement Emergency Department-Initiated Buprenorphine for Opioid Use Disorder (UH3 DA047003-02)	National Institute on Drug Abuse	04/2019-8/2023
Corita R. Grudzen, M.D., principal investigator; Fernanda Bellolio, M.D., M.S., site principal investigator	PRIM-ER: Primary Palliative Care for Emergency Medicine (UH3 AT09844-02)	National Center for Complementary and Integrative Health	07/2019-07/2023
Kalyan S. Pasupathy, Ph.D., principal investigator; Fernanda Bellolio, M.D., M.S., co-investigator	IDEA-LL: Improving Diagnosis in Emergency and Acute Care-Learning Laboratory (R18HS26622-2)	Agency for Healthcare Research and Quality	07/2018-06/2023
W. Michael Hooten, M.D., principal investigator; Molly M. Jeffery, Ph.D., co-investigator	Unintended Prolonged Opioid Use (U01 TR002743-01)	National Center for Advancing Translational Sciences	03/2019-02/2023
Sundeep Khosla, M.D., principal investigator; Molly M. Jeffery, Ph.D., co-investigator	Center for Clinical and Translational Science (CCaTS) Administrative Supplement: Decision Support for Pain Management in Primary Care	National Center for Advancing Translational Sciences	09/18/2017-06/30/2022
Nathan W. Cummins, M.D., principal investigator; Fernanda Bellolio, M.D., M.S., site co-principal investigator	Angiotensin Receptor Blockers for Novel SARS-CoV-2: A Multicenter Randomized Control Trial (P008672201)	Minnesota Partnership for Biotechnology and Medical Genomics	04/15/2020-04/14/2022
Pinar Karaca-Mandic, Ph.D., principal investigator; Molly M. Jeffery, Ph.D., site principal investigator	Biosimilars: Policy, Insurance and Implications for Cancer Patients (RSGI-17-154-01)	American Cancer Society	01/2018-12/2021
Pinar Karaca-Mandic, Ph.D., principal investigator; Molly M. Jeffery, Ph.D., co-investigator	Medical Reversals: Deimplementing Ineffective and Unsafe Treatments (R01 0HS25164-3)	Agency for Healthcare Research and Quality	09/2017-08/2021
Molly M. Jeffery, Ph.D., principal investigator	Acute Pain Pathways	Food and Drug Administration	2019-2021
Fernanda Bellolio, M.D. M.S., principal investigator	REDEEM: Recognizing Delirium in Emergency Medicine	Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery	06/2019-06/2020
Matthew A. Rank, M.D., principal investigator; Molly M. Jeffery, Ph.D., site principal investigator	Step-Down of Asthma Biologics in Real-World Practice Settings (R21 HL140287-02)	National Heart, Lung, and Blood Institute	08/2018-06/2020
Robin E. Bryde, M.D., co-principal investigator; Brian P. Shapiro, M.D., co-principal investigator; Andrea C. Sharp, M.D., co-investigator	Characterizing Left and Right Ventricular Function in Relation to Exercise Capacity in Breast Cancer Survivors	Mayo Clinic Department of Cardiovascular Diseases	01/2020-12/2020
Johnathan (John) M. Sheele, M.D., M.H.S., M.P.H., principal investigator	Research Accelerator for Clinicians Engaged in Research Program (RACER)	Mayo Clinic	01/2020-12/2020
Molly M. Jeffery, Ph.D., principal investigator	Harms Associated With Unsafe Prescribing of Opioids Subject to REMS	U.S. Food and Drug Administration	2019-2020
Michael P. Boniface, M.D., principal investigator	Patient-Centered Outcomes Following Implementation of a Point-of-Care Ultrasound Curriculum for Internal Medicine Residents: An Exploratory Study	Endowment for Education Research Award	01/2019-12/2019
Andrea C. Sharp, M.D., principal investigator	Research Accelerator for Clinicians Engaged in Research Program (RACER)	Mayo Clinic	01/2019-12/2019
Molly M. Jeffery, Ph.D., principal investigator	Addressing Unsafe Prescribing of Opioids Subject to REMS: Prevalence	Food and Drug Administration	2018-2019
Laura E. Walker, M.D., principal investigator	Shared Decision-Making to Improve Goals of Care Discussions in Elderly Emergency Department Patients	Emergency Medicine Foundation	2017-2018
Jana L. Anderson, M.D., principal investigator	Shared Decision-Making in Parents of Children With Acute Otitis Media: The Acute Otitis Media Choice Trial (FP00087437)	Emergency Medicine Foundation	07/01/2016-12/31/2018
Pinar Karaca-Mandic, Ph.D., principal investigator; Molly M. Jeffery, Ph.D., co-investigator	Diffusion of Clinical Evidence into Practice: Physician Networks, Delivery Organizations, and Markets (R56 HL130496-01)	National Heart, Lung and Blood Institute	09/2016-08/2018
J. Donald Easton, M.D., principal investigator; Fernanda Bellolio, M.D., M.S., site principal investigator	Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial (U01NS062835-06)	National Institute of Neurological Disorders and Stroke	05/01/2017-04/30/2018
Casey M. Clements, M.D., Ph.D., site principal investigator	Emergency Department Sepsis Program Sample Repository: Biomarker Discovery for Prognosis and Risk Stratification of Undifferentiated Sepsis Patients Presenting to the Emergency Department	The Antioch Foundation	04/2013-03/2016
Casey M. Clements, M.D., Ph.D., principal investigator	Fluoroquinolone Resistance and Patient Outcomes in Patients with E. Coli	The Antioch Foundation	02/2014-02/2016
Scott M. Silvers, M.D., principal investigator	A Randomised, Double-Blind, Parallel-Group Placebo-Controlled Phase III Study to Evaluate the Efficacy and Safety of Desmoteplase in Subjects With Acute Ischemic Stroke	Lundbeck	2012-2014
Michael M. Mohseni, M.D., principal investigator	Runners' Science	Mayo Clinic	2008-2011

James H. and Helen F. Crossingham Emergency Medicine Award

Jana L. Anderson, M.D., is the most recent awardee of the James H. and Helen F. Crossingham Emergency Medicine Award. Dr. Anderson is a consultant and researcher with a specialty in the care of children. She has used the award to advance her research skills and knowledge in acute pain management for children.

With support from the Crossingham award, Dr. Anderson has completed the first phase of the PEdiatric Acute Pain and OpioiD (PEAPOD) project. The initial phase included a description of the prevalence of pediatric pain in the emergency department and the trends of pediatric opioid use in the emergency department. In addition to opioids, researchers working on the PEAPOD project are examining evidence for low-dose ketamine for children as an opioid alternative for pain management.

The next phase of the PEAPOD project began in 2020. In this phase, researchers are looking at factors of opioid use in children that may contribute to opioid abuse. The study is examining opioid prescriptions from sources across the nation. The goal is to identify any factors that may lead to repeat opioid prescriptions in children.

The Mayo Clinic Division of Emergency Medicine Research thanks Mr. and Mrs. Crossingham for this faculty development award. Dr. Anderson's faculty development and associated research strengthens the department and will have a lasting impact on acute care delivery for children at local and national levels.