About the Core

In 1994, Mayo Clinic started its Biomedical Mass Spectrometry Laboratory to analyze stable-isotope-labeled samples generated from metabolic studies performed in the General Clinical Research Center (GCRC).

The GCRC was transformed to facilitate the translation of basic discoveries into clinical practice to improve human health with funding from the Mayo Clinic Center for Translational Science Activities (CTSA). Additionally, the Biomedical Mass Spectrometry Laboratory was transformed into the Metabolomics Core, to complement the Bioinformatics Core, Proteomics Core and Genome Analysis Core, based on an assessment of need by Mayo Clinic surveying investigators.

In 2009, the Metabolomics Core was awarded an American Recovery and Reinvestment Act (ARRA) grant (UL1RR024150-04S2, Development of Novel Metabolomics Methodologies) to develop and to establish qualitative and quantitative metabolite measurements.

In 2013, the CTSA became the Center for Clinical and Translational Science (CCaTS).

Also in 2013, Mayo Clinic was one of three centers awarded a five-year NIH-sponsored Regional Metabolomics Resource Cores grant, joining three centers that received the award in 2012.


National Institutes of Health (NIH) Public Access Policy requires that all publication that results from NIH funding be uploaded to PubMed Central. Review the process for uploading publications.

All users of the core must cite the Mayo Clinic Metabolomics Resource Core grant as a funding source in any resulting publications. Use this language:

This publication was made possible by Mayo Clinic Metabolomics Resource Core through grant number U24DK100469 from the National Institute of Diabetes and Digestive and Kidney Diseases and originates from the National Institutes of Health Director's Common Fund.