The Gene Expression Core (GEC), part of the Advanced Genomics Technology Center at Mayo Clinic, is a state-of-the-art laboratory for the analysis of gene expression.

Created in 2000 to serve the needs of Mayo Clinic researchers in Rochester, Minn., Jacksonville, Fla., and Phoenix-Scottsdale, Ariz., the GEC now provides genomic services to investigators across the globe.

What we do

  • mRNA gene expression profiling by microarray, qPCR and next-generation sequencing
  • miRNA profiling by microarray, qPCR and next-generation sequencing

Samples accepted

  • RNA from fresh-frozen tissues; formalin-fixed, paraffin-embedded tissues; laser-capture microdissected cells; cell lines; and blood cells

New in the GEC

  • Fluidigm BioMark qPCR mRNA
  • Fluidigm BioMark qPCR miRNA
  • Illumina TruSeq mRNA next-generation sequencing
  • Illumina TruSeq miRNA next-generation sequencing


  • Minnesota Partnership for Biotechnology and Medical Genomics
  • Mayo Clinic Division of Biomedical Statistics and Informatics
  • Sequencing Core at Mayo Clinic
  • Genotyping Core at Mayo Clinic

Mayo Clinic support

  • Fees for services
  • Center for Individualized Medicine
  • Cancer Center
  • Research Core Oversight Subcommittee