The Biomaterials and Histomorphometry Core at Mayo Clinic processes samples from small and large animal studies including metal and polymer implants, providing vital services for basic science and clinical investigators.

Overview

The Biomaterials and Histomorphometry Core at Mayo Clinic processes samples from small and large animal studies including metal and polymer implants, providing vital services for basic science and clinical investigators in the areas of biochemistry, cardiology, endocrinology, gastroenterology, molecular medicine, nephrology, neurology, orthopedics, otorhinolaryngology, radiology and many others.

For more than 40 years, the core has prepared and measured over 6,000 human biopsies and generated a unique histomorphometry database for human iliac crest biopsies from specimens obtained from recruited females and males with healthy bone metabolism. The core has expanded into regenerative medicine service lines, which include processing tissues with hard material implants that include metal and scaffolds as well as cGMP applications involving small and large animal models.

The Biomaterials and Histomorphometry Core also provides validated bone histologic and histomorphometric services in accordance with The American Society for Bone and Mineral Research (ASBMR) nomenclature for the diagnosis and management of metabolic bone disorders.

The Biomaterials and Histomorphometry Core supports investigators inside and outside Mayo Clinic resulting in many successful projects from industry, the Department of Defense and the National Institutes of Health. The core has also supported several national programs including multiyear consortium grants.

Accreditations and certifications

The Biomaterials and Histomorphometry Core is accredited and certified by these organizations:

  • Clinical Laboratory Improvement Amendments (CLIA)
  • College of American Pathologists (CAP)
  • Good Laboratory Practice (GLP)
  • Mayo Clinic Quality Fellows Program

Directed by Michael J. Yaszemski, M.D., Ph.D., and Avudaiappan (Avudai) Maran, Ph.D., the Biomaterials and Histomorphometry Core provides services to all Mayo Clinic faculty and staff. Additionally, services are offered to investigators and research collaborators outside Mayo Clinic. For more information, please contact the core.