Transcranial magnetic stimulation

Displaying 11 studies

  • rTMS for Depressed Teens: A Sham-Controlled Trial, Part 2 Rochester, MN

    This research proposal aims to better understand the neurobiology of depression in adolescents and how repetitive transcranial magnetic stimulation (rTMS) may therapeutically impact brain function and mood. This investigation also proposes the first study to examine the efficacy of rTMS maintenance therapy in adolescents who have met clinical criteria following acute rTMS treatment. The magnetic resonance (MR) spectroscopy pattern of rTMS response will be analyzed according to previously established protocols.

  • Cathodal tDCS in MCI: A Randomized, Double-Blind, Sham-Controlled Pilot Study Scottsdale/Phoenix, AZ

    The purpose of this study is to investigate whether giving transcranial direct current stimulation (tDCS) treatment using an investigational device called the Soterix tES Device (tDCS device) on the right side of the brain can improve performance on cognitive tests. Investigational means that the tDCS device is not approved by the U.S. Food and Drug Administration (FDA) for the use in this study.

  • An Open Label Trial of TMS Therapy for Bipolar Depression Rochester, MN

    Transcranial Magnetic Stimulation (TMS) is an increasingly accepted neurostimulation- based treatment for major depressive disorder. While there is a growing anecdotal database supporting its use in bipolar depression the investigators propose to collect open label efficacy and safety data in a small population of patients with clinically verified bipolar disorder.

  • A Study of Brain Chemistry in Depressed Patients Compared to Healthy Patients Who are not Depressed Rochester, MN

    The purpose of this study is to study brain chemistry in depressed patients compared to healthy patients who are not depressed.

  • Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy Rochester, MN; Jacksonville, FL

    The purpose of this study is to evaluate effectiveness, safety, and tolerability of repeated, daily sessions with the STARSTIM device, which delivers transcranial cathodal direct current stimulation (tDCS). Subjects will be treated with STARTSTIM or sham device for 10 sessions over a 2-week period. The subjects will be followed for an addietional 10 weeks post treatment. Quality of Life questionnaires and adverse events will be collected and evaluated.

  • Cortical Excitability and Inhibition in MDD Rochester, MN

    The purpose of this study is to learn if measures of brain activity are different in children and adolescents with depression who are in different stages of treatment. This is important because it may identify a biological marker for depression that could one day be used to identify depressed children who would benefit from certain treatments (medications for example), or to monitor how well treatments are working. Brain activity measures(known as cortical excitability and inhibition) will be collected by Transcranial Magnetic Stimulation (TMS). TMS is a noninvasive (no surgery or implants) brain stimulation technology which can make parts of the ...

  • Adaptive Design Study of NEST sTMS in Subjects With Major Depressive Disorder Rochester, MN

    This is a double-blind, sham controlled, multi-center study to confirm the safety and efficacy of synchronized transcranial magnetic stimulation (sTMS) for the treatment of patients currently experiencing an episode of depression who have failed to respond to at least one (1) antidepressant medication. Patients will be randomly assigned to either active or sham therapy and will undergo daily treatments for a period of time. Following completion of blinded treatments, patients may be eligible for a course of open label treatments.

  • Study of Repetitive Transcranial Magnetic Stimulation (rTMS) in Depressed Teens Rochester, MN

    This research study aims to test the safety and effectiveness of repetitive transcranial magnetic stimulation (rTMS) on teens with depression. The study also seeks to understand how rTMS treatment affects the neurobiology of teens with depression.

  • Safety and Effectiveness of NeuroStar® Transcranial Magnetic Stimulation (TMS) Therapy in Depressed Adolescents Rochester, MN

    To evaluate the safety and efficacy of daily, active Neurostar® TMS (when compared with sham treatment) in adolescents meeting criteria for Major Depressive Disorder (MDD).

  • A Study of Repetitive Transcranial Magnetic Stimulation as a Treatment for Depression Added to Standard Care Rochester, MN

    The purpose of this study is to systematically investigate the use of repetitive transcranial magnetic stimulation (rTMS) as an added treatment for patients who have depression that is not decreasing with standard care.

  • Adolescent Biomarker Guided rTMS Rochester, MN

    The purpose of this study is to gather information regarding the use of rTMS as a treatment for depression in adolescents with Major Depressive Disorder. The investigators also hope to learn if measures of brain activity (cortical excitability and inhibition) collected with transcranial magnetic stimulation (TMS) can be used to identify which patients will benefit from certain types of rTMS treatment. 


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