Clinical Trials

The primary purpose of this study is to prospectively assess symptoms of bloating (severity, prevalence) in patients with diabetic gastroparesis.

To understand the utility of measuring stomach emptying, symptoms during a stomach emptying, and blood markers of body metabolism.

The purpose of this study is to objectively measure gastric motility during a standardized test meal, and over the full course of the WPS test, identify patients with delayed gastric emptying as accurately as a scintigraphic gastric emptying scan.

This study will see if a new wireless patch system (WPS) will be able to objectively measure gastric, small intestine and colonic motility in patients with chronic nausea and vomiting and identify patterns that help distinguish common gastric sensorimotor disorders

The purpose of this study is to evaluate the effects of tradipitant relative to placebo in healthy volunteers:

• Difference in fasting GV;
• Difference in postprandial GV and in accommodation volume (that is, postprandial minus fasting gastric volumes);
• Difference in gastric emptying (T1/2, emptying at 2h and emptying at 4h);
• Volume to fullness (sensation of usual postprandial fullness) and maximum feeling of fullness (MTV).

The purpose of this study is to evaluate the dose-dependent effects of TAK-954 on gastric emptying time of solids in participants with diabetic or idiopathic gastroparesis assessed by scintigraphy.

The purposes of this study are to assess gastric motility and emptying with scintigraphy in patients with upper gastrointestinal symptoms, to evaluate the relationship between daily symptoms and GE, motility, and symptoms during a GE study, to assess fasting and postprandial gastric volumes and motility with MRI in patients with upper gastrointestinal symptoms, and to compare gastric motility measured with scintigraphy and MRI.

The aim of this study is to compare baseline, early post-procedural (2 month), and delayed post-procedural (6 month) T1/2, as assessed by both GEBT and NSSM, in seven adult subjects with obesity who have underwent an Endoscopic Gastric Remodeling Weight Loss procedure (EGRWL).  

The purpose of this study is to establish a new protocol and normative values for evaluating gastric emptying and accommodation in bariatric surgery patients.

The purpose of this study is to understand changes in gastric electrical activity and gastric emptying in response to the Spatz3 balloon and evaluate if baseline measurement of these gastric physiological changes can predict response to treatment, and to understand the impact that balloon volume adjustment after weight loss plateau has on gastric electrical activity and emptying and correlate these changes with effectiveness of the balloon volume adjustment in resulting in further weight loss after the balloon.

The purpose of this study is to explore the effectiveness and safety of a modified gastroplication technique for weight loss in five patients with obesity, and includes physiologic appraisal of gastric emptying (via gastric emptying breath test) and post-prandial gastric accommodation (via SPECT).