Subharmonic Aided Pressure Estimation Of Portal Hypertension
Rochester, MN
The purpose of this study is to determine the reproducibility of the SHAPE algorithm across two different ultrasound contrast agents in the same subjects to estimate portal pressures with a Logiq E10 state-of-the-art ultrasound scanner (GE Healthcare). Examine if serial SHAPE every 6 ± 2 months can accurately predict development of ascites and other liver related events in patients with compensated cirrhosis undergoing routine hepatocellular carcinoma surveillance in a multi-center setting. Use SHAPE to monitor treatment response (in particular non-selective beta blockers) in patients identified with portal hypertension and compare results to elastography measurements, or clinical outcomes (i.e., rate of esophageal ...