Clinical Trials

Determine the effect of endocrine pancreas morphology, turnover and dedifferentiation on glucose tolerance in humans. 

The purpose of this study is to determine the effects of transient insulin deprivation in people with type 1 DM (T1DM) and Total Pancreatomy on synthesis of specific plasma proteins applying stable isotope-proteome approach.

The standard of care for a patient with resectable pancreatic is to perform pancreatic resection which, even in the modern era is associated with significant complications and impact on quality of life, often in the setting of poor survival even in the best scenario. Currently, there is a lack of data on patient quality of life after such procedures, how quality of life changes throughout the course of care, and whether patients who undergo these procedures are satisfied with their decision. This research is aimed to understand the impact of pancreatic surgery on patients' quality of life, how that impact ...

The purpose of this study is to estimate the risk of diabetes related complications after total pancreatectomy.  We will contact long term survivors after total pancreatectomy to obtain data regarding diabetes related end organ complications.

The purpose of this study is to evaluate if a lidocaine infusion during surgery will provide benefit to pancreatectomy patients in regards to analgesia and return of bowel function.

The prupose of this study is to compare estimated blood loss and measured blood loss in pancreaticoduodenectomies.

The purpose of this study is to to determine the individual treatment effect of somatostatin and whether duration of antibiotic therapy coupled with octreotide provides improved outcomes after pancreaticoduodenectomy. 

The objectives of this study are to reduce the rate of bacterobilia driven surgical site infection (SSI) in patients undergoing pancreatic head resection by providing surgical team with NS data in the post-operative setting, and to reduce cost of care through reduction in SSI and improved antibiotic stewardship.

The aims of this study will be collection of standard and routinely obtained data specifically in the preoperative evaluation, operative room, postoperative/hospitalization period, and long term follow from the electronic medical record.  Data collected will then be analyzed with standard scientific methods. 

The investigators believe that the lessons learned from studies regarding 30-day and 90-day readmission are primarily due to failure of early symptom recognition, and medical error. Through the aid of remote monitoring and early symptom detection, the hypothesis for the current proposal is that interventions can be recommended in an earlier, remote fashion that may result in earlier post-surgical discharge, prevent decompensation, and prevent increased readmissions that have been associated with decreased LOS in other surgical populations.