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Follow-up of Surgically Repaired Ventral (Abdominal) Hernias
Rochester, MN
The purpose of this study is to compare the results of different types of repair: open vs. laparoscopic, mesh vs. no mesh, and the type of mesh versus other mesh products over a 10 year period.
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Study Of AGN-151607-DP To Assess Adverse Events And Change In Disease Activity In Adult Participants Undergoing Open Abdominal Ventral Hernia Repair
Rochester, MN
A ventral hernia happens when the muscles in the front of your belly become weak and let abdominal content push through, causing a bulge. If it gets worse, intestines can slip into the bulge, leading to serious pain and health problems. This study aims to asses if AGN-151607-DP is safe and effective for closing the belly wall after open ventral hernia surgery, without needing a complex procedure. Adverse Events and change in disease activity will be assessed.
AGN-151607-DP is an investigational drug being developed to treat ventral hernia. Participants will be randomly placed in treatment groups to receive either AGN151607-DP or ...
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A Study to Compare Patient Reported Outcomes in the Belsey Mark-IV and Nissen fundoplication Procedures in Patients with Large Hiatal Hernia
Rochester, MN
The goal of this study is to compare the rate of recurrence of hiatal hernia in patients with large hiatal hernias who had the Belsey Mark-IV and Nissen fundoplication procedures.
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Study of Metabolic, Phenotypic and Microbiome Profiling in Fetal Tracheal Aspirate and Amniotic Fluid after Fetal Surgery
Rochester, MN
The purpose of this study is to investigate the microbial, protein, genetic and cell profiles of the tracheal aspirates and amniotic fluid in human fetuses with congenital diaphragmatic hernia that undergo fetal therapy.