Endoscopic mucosal resection

Displaying 7 studies

  • Prospective Evaluation of Budesonide for Prevention of Esophageal Strictures after Endotherapy Jacksonville, FL

    Surgery has been historically the mainstay treatment for advanced pre-malignant lesions and early esophageal cancers. However, esophagectomy is associated with significant morbidity and mortality. With the advance of therapeutic endoscopy, there has been a growing interest and application of endoscopic resection and mucosal ablative techniques for the treatment of these diseases. Esophageal stricture(ES) formation has become an increasingly recognized complication of extensive endoscopic mucosal ablation and/or resection. The resultant symptomatic stricture development can significantly impair a patient's quality of life. Endoscopic therapy of esophageal strictures with balloon dilation and/or local steroid injection is invasive, costly, and associated with the potential ...

  • Performance of Clutch Cutter vs. Conventional Endoscopic Submucosal Dissection Methods among Gastroenterology Trainees in an Ex Vivo Model Rochester, MN

    The purpose of this study is to assess for differences between Clutch Cutter vs. conventional endoscopic submucosal dissection techniques with regards to; Time to incision; Time to dissection; Total procedure time; Number of perforations; and Ease of use as determined by participant questionnaire.

  • A Study of Conforcal Fluorescent Microscopy in Barrett's Esophagus Tissue from Clinically-Indicated Endoscopic Resection Rochester, MN; Scottsdale/Phoenix, AZ

    The purpose of this study is to test the performance characteristics of Optiscan, a handheld confocal fluorescent microscopy system, along with Ninepoint and Cellvizeo a probe based confocal microscopy system in ex-vivo Barrett’s esophagus tissue obtained from clinically-indicated, endoscopic mucosal resection (EMR) in patients scheduled for clinically indicated surveillance of Barrett's Esophagus.

  • Cold Snare EMR Trial Jacksonville, FL

    The primary aim of the study is to compare safety and effectiveness of two methods of endoscopic resection of large colorectal polyps: cold snare EMR (without electrocautery) vs. hot snare EMR (with electrocautery).

  • Endoscopic Mucosal Resection and Cellular Matrix Rochester, MN

    This study is being done to assess the use of scaffold products in promoting constructive healing as determined by the ability of the resection site to lift during follow-up.

  • A Study of the Safety of Using SIC 8000 in Patients Undergoing Endoscopic Mucosal Removal of Colon Lesions Equal to or Larger Than 2 cm Jacksonville, FL

    The purpose of this study is to assess the effectiveness of SIC 8000 injected into the submucosa under polyps, adenomas, early-stage cancers or other gastrointestinal mucosal lesions to provide a lift to them prior to grasping and cutting with a snare during endoscopic removal procedures.

  • Soft Coagulation for the Prevention of Adenoma Recurrence Jacksonville, FL

    The purpose is to investigate whether a simple additional treatment applied during colonoscopy (called 'soft' coagulation) can reduce the risk of recurrence of polyp at the area where the polyp was removed. After a large polyp is removed it is known that there is a 20% chance that a small recurrence of polyp occurs at the site of removal can occur within 5 months of the polyp being removed. This in theory will burn off tiny polyp tissue, which is usually not visible to the naked eye. This additional treatment may possibly reduce the risk of polyp recurrence.


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