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miRNA Expression in Aneurysm Healing
Rochester, MN
The purpose of this study is to determine if vascular remodeling may be impacted by concomitant coiling with flow diverter therapy. We will compare micro-RNA markers between groups of patients treated with and without concomitant coiling with flow diversion therapy.
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A Study To Explore The Renal Safety Of Visipaque Injection 320 MgI/mL In Patients With Chronic Kidney Disease
Rochester, MN
This parallel-group, randomized, placebo-controlled study will examine the incidence and severity of acute kidney injury (AKI) in patients with chronic kidney disease (CKD) stage III/IV following an i.v. injection of iso-osmolar iodinated contrast material iodixanol (Visipaque™ Injection 320 mgI/mL), as compared with patients who received saline and underwent a non-enhanced CT (NECT) and duplex ultrasound (US) during their scheduled post-EVAR surveillance imaging.
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A Study to Assess Temporal Changes in Reintervention Rate and the Impact of Reinterventions after Endovascular Aortic Repair (EVAR)
Rochester, MN
The purposes of this study are to determine temporal changes in patient reported outcomes and quality of life (QOL) associated with EVAR, factors associated with requirement for reintervention after EVAR, and the effect of reinterventions on patient reported outcomes and QOL associated.
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Clinical Research Study With Clazosentan To Evaluate Its Effects On Preventing Complications Due To The Narrowing Of The Blood Vessels (Vasospasm) In The Brain, Caused By Bleeding Onto The Surface Of The Brain (REACT)
Jacksonville, FL
The purpose of this study is to evaluate if clazosentan (on top of normal routine medical care) can reduce the risk of developing complications related to cerebral vasospasm and permanent brain damage as compared to normal routine medical care alone.