Brain tumor, breast cancer, colon cancer, congenital heart disease, heart arrhythmia. See more conditions.
(for at least one location)
Describes the nature of a clinical study. Types include:
The purpose of this study is threefold: the first aim is to use patient-derived fresh tumor tissue to create cell lines and 3D tumor models (i.e. organoids) that preserve the characteristics of the original tumor. The preservation of the original tumor's drug resistance/response profile will be a major focus of this aim. The second aim is to conduct high-throughput testing of various drugs (e.g., virotherapy, immunotherapy) on these cell lines and 3D tumor models. The completion of the second aim is an important step towards developing a platform that can help guide treatment decisions for future patients, based on the drug response observed in the cell lines and 3D tumor models. The third aim is to use pan-omics approaches (i.e., genomics, proteomics, metabolomics) to find markers of drug response based on the results of the high-throughput drug testing on the cell lines and 3D tumor models.
Study statuses change often. Please contact us for help.
Open for enrollment
The purpose of this study to collect blood samples and data to assess the diagnostic capability of an updated version of the Prospera™ test. The current standard of care for detection of rejection in renal allograft recipients is serum creatinine, often used in combination with other blood tests such as proteinuria. Natera has developed an assay called Prospera™ to detect the amount of donor-derived cell-free DNA (dd-cfDNA), which is a marker of kidney rejection.
Scottsdale/Phoenix, AZ, Rochester, MN
The purpose of this study is to analyze the effect of parity, menopause and reproductive lifespan on kidney structure and function.
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