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(for at least one location)
Scottsdale/Phoenix, AZ, Rochester, MN
Describes the nature of a clinical study. Types include:
The goal of this research is to identify risk profiles of women (with particular emphasis on Hispanic women) for breast cancer based on family history, breast density and other factors known to impact risk such as age, weight, age at menarche, age at birth of first child, etc.
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Rochester, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL
A group of doctors and scientists led by Dr. Fergus Couch at the Mayo Clinic in Rochester, Minnesota, are conducting this study to advance our understanding of how breast cancer is inherited through families. Genetic testing of breast cancer genes is often done to find the cause of breast cancer tracking through families. Testing often identifies deleterious (cancer causing) mutations and Variants of Uncertain Significance (VUS), that may or may not cause breast cancer. Because of uncertainties about the meaning of many of these results, patients and their family members often cannot benefit from the knowledge that they have one of these mutations. In this study we aim to establish the risks of cancer for deleterious mutations and VUS in each of the clinically tested breast cancer genes, so that families and their health care providers can better manage their risk of breast cancer. To answer these questions, we plan to use mutation results from genes currently included on genetic testing panels for breast cancer, along with information on the history of cancer in families and on breast cancer risk factors collected using a questionnaire.
Open for enrollment
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