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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 31 for Obesity

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  • Study status: Open/Status Unknown
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  1. Transforming Non-Invasive Liver Disease Detection by Magnetic Resonance Elastography

    Rochester, MN

  2. The Development of a Shared Decision Making Encounter Tool for Weight Management Decisions

    Rochester, MN

  3. A Study to Analyze the Role of Eosinophils in Human Adipose Tissue Metabolism

    Scottsdale/Phoenix, AZ

  4. A Study to Evaluate Individualized Lifestyle Intervention for Obesity Management Based on Obesity Phenotypes

    Rochester, MN

  5. A Study of Individualized Obesity Pharmacotherapy Based on Obesity Phenotypes

    Rochester, MN

  6. A Study to Evaluate Setmelanoitide to Treat Patients with Rare Genetic Disorders of Obesity

    Rochester, MN

  7. A Study to Evaluate the Effectiveness and Safety of Aramchol Versus Placebo in Subjects With NASH (ARMOR)

    Rochester, MN

  8. A Study to Determine the Feasibility of Primary Care Referrals to Community-based Lifestyle Programs for Obesity Management

    Rochester, MN

  9. Bariatric Surgery Versus Diet Alone in the Bile Acid Pathway and Weight Loss

    Rochester, MN

  10. Effect of 12-Week Vegetarian Diet Intervention on Inflammatory Status and Cardio-Metabolic Parameters

    Rochester, MN

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