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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 17 for Liver disease

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  • Study status: Open/Status Unknown
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  1. Transforming Non-Invasive Liver Disease Detection by Magnetic Resonance Elastography

    Rochester, MN

  2. A Study to Evaluate the Effectiveness and Safety of CC-90001 in Subjects With Non-alcoholic Steatohepatitis (NASH) and Stage 3 or Stage 4 Liver Fibrosis

    Scottsdale/Phoenix, AZ

  3. Pulmonary Rehabilitation in End-Stage Liver Disease

    Scottsdale/Phoenix, AZ, Rochester, MN

  4. A Study to Evaluate the Alfapump® System in the Treatment of Refractory or Recurrent Ascites

    Rochester, MN, Scottsdale/Phoenix, AZ

  5. A Study to Evaluate Dupilumab as a Treatment for Moderate-to-Severe, Chronic Hepatic Pruritus

    Jacksonville, FL

  6. Study Investigating the Activity of Vidofludimus Calcium as a Treatment for Primary Sclerosing Cholangitis (PSC)

    Scottsdale/Phoenix, AZ, Rochester, MN

  7. Treating Adult Patients with Primary Sclerosing Cholangitis with Oral Vancomycin in a Randomized Trial

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity- AIM 2

    Scottsdale/Phoenix, AZ

  9. A Study of Short-term Survival in Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5%

    Rochester, MN

  10. A Study of Evaluating the Use of Ultrasound Shear Wave Imaging in Patients with Liver Fibrosis

    Rochester, MN

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