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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-8 of 8 for High blood pressure (hypertension)

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate the Effect of Latanoprostene Bunod Ophthalmic Solution 0.024% on Episcleral Venous Pressure and Outflow Facility in Participants With Ocular Hypertension

    Rochester, MN

  2. HELP-HY: Health Education and sLeep Program in HYpertension

    Rochester, MN

  3. Sleep Extension and Blood Pressure

    Rochester, MN

  4. Physiologic Effects of Sleep Restriction

    Rochester, MN

  5. A Study to Determine Effectiveness and Safety of Ultrasound Shockwave Therapy for Post-Stenotic Microvascular Modeling

    Rochester, MN

  6. A Study to Evaluate the Effectiveness and Safety of Remdesivir to Treat Coronavirus Disease 2019 in an Outpatient Setting

    Rochester, MN

  7. Neural Circulatory Control and SUDEP Risk.

    Rochester, MN

  8. A Study to Evaluate the Impact of Menopause on Blood Pressure Regulation During Exercise

    Rochester, MN

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