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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-7 of 7 for Back pain

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  • Study status: Open/Status Unknown
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  1. Transforaminal Lumbar Interbody Fusion (TLIF)

    Rochester, MN

  2. Study Evaluating the Side Effects of Bone Marrow-Derived Stem Cells When Injected Into the Facet Joints for the Treatment of Painful Arthropathies

    Jacksonville, FL

  3. A Study to Evaluate the Effectiveness of Tuina in Managing Chronic Low Back Pain

    Rochester, MN

  4. Low-Cost Tool for Compliance and Treatment-Tracking of Low Back Pain Patients

    Rochester, MN

  5. Dorsal spinal cord stimulation vs medical management for the treatment of low back pain

    Rochester, MN

  6. A Study to Evaluate the Safety and Feasibility of Platelet-rich Plasma to Treat Facetogenic Low Back Pain

    Rochester, MN

  7. A Study to Evaluate Performance Outcomes Following Interventional Treatment of Axial Low Back Pain

    Jacksonville, FL

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