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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 10 for Ulcerative colitis

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  • Study status: Open/Status Unknown
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  1. Pharmacokinetics and Pharmacodynamic Biomarkers of Janus Kinase Inhibitor Therapy in Patients with Ulcerative Colitis (PROPHETIC Study)

    Rochester, MN

  2. The Influence of Diet on Gut Microbiotas

    Rochester, MN

  3. A Study to Evaluate GB004 to Treat Patients with Mild-to-Moderate, Active Ulcerative Colitis

    Rochester, MN

  4. A Study to Assess the Effectiveness and Safety of Golimumab in Pediatric Participants With Moderately-to-Severely Active Ulcerative Colitis

    Rochester, MN

  5. A Study to Evaluate Intra-arterial Delivery of Mesenchymal Stem Cells for Luminal Ulcerative Colitis

    Rochester, MN

  6. A Study to Evaluate the Effectiveness and Safety of Risankizumab in Subjects with Moderately-to-Severely Active Ulcerative Colitis

    Rochester, MN

  7. A Study to Assess the Effectiveness and Safety of Risankizumab in Subjects with Ulcerative Colitis

    Rochester, MN

  8. Improving the Quality of Care for Adults with Inflammatory Bowel Disease

    Jacksonville, FL

  9. A Study to Evaluate Impact of COVID-19 on Inflammatory Bowel Disease

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Mayo Clinic Inflammatory Bowel Disease Repository

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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