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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 34 for Crohn's disease

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  • Study status: Open/Status Unknown
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  1. Trial of Specific Carbohydrate and Mediterranean Diets to Induce Remission of Crohn's Disease

    Rochester, MN

  2. Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

    Jacksonville, FL

  3. An Extension Study of Oral Ozanimod for Moderately-to-Severely Active Crohn's Disease

    La Crosse, WI

  4. A Study to Evaluate the Effectiveness and Safety of TD-1473 in Crohn's Disease

    Scottsdale/Phoenix, AZ

  5. A Study of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

    La Crosse, WI

  6. Filgotinib in the Induction and Maintenance of Remission in Adults With Moderately to Severely Active Crohn's Disease

    Rochester, MN

  7. A Study of Adult Allogeneic Expanded Adipose-derived Stem Cells (eASC) for the Treatment of Complex Perianal Fistula(s) in Patients With Crohn's Disease

    Jacksonville, FL

  8. A Study of Oral Ozanimod as Maintenance Therapy for Moderately-to-Severely Active Crohn's Disease

    La Crosse, WI

  9. Stem Cell Coated Fistula Plug in Patients With Crohn's RVF

    Rochester, MN, Rochester, MN

  10. A Study to Assess the Efficacy and Safety of Risankizumab in Subjects With Moderately to Severely Active Crohn's Disease Who Failed Prior Biologic Treatment

    Rochester, MN, Rochester, MN

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