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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-8 of 8 for Irritable bowel syndrome

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate the Safety and Efficacy of ABT-494 for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis

    Rochester, MN

  2. Endpoint Determination Study Protocol

    Jacksonville, FL

  3. A Study Evaluating the Use of Implementing a Low FODMAP Diet in Irritable Bowel Syndrome Patients

    Jacksonville, FL

  4. A Study Using Biomerica InFoods® IBS Test in Patients with Irritable Bowel Syndrome (IBS)

    Scottsdale/Phoenix, AZ

  5. A Biobank for Functional Gastrointestinal Disorders (FGID)

    Rochester, MN

  6. Obesity and IBS as likely associated comorbidities

    Scottsdale/Phoenix, AZ

  7. Bile Acids, Genetic Control and Ileo-Colonic Mucosal Expression in IBS-D

    Rochester, MN

  8. Mucosal and Microbiota Changes During Acute Campylobacteriosis

    Rochester, MN


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