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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-8 of 8 for Gastroesophageal reflux disease (GERD)

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  • Study status: Open/Status Unknown
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  1. A Study of of IW-3718 in Patients with Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors

    La Crosse, WI, Jacksonville, FL

  2. A Study to Evaluate the Safety and Effectiveness of Endoluminal Clinical Treatment of Gastroesophageal Reflux Disease

    Jacksonville, FL

  3. A Study to Evaluate the Effectiveness of Diaphragmatic Breathing on Reflux Symptoms in Outpatients

    Jacksonville, FL

  4. Laryngopharyngeal Reflux before and after Cricopharyngeal Myotomy

    Scottsdale/Phoenix, AZ, Rochester, MN

  5. A Study to Evaluate Long-Term Outcomes of Gastroesophageal Reflux Disease (GERD)

    Rochester, MN

  6. A Study to Evaluate Minimally Invasive Molecular Approaches for the Diagnosis of Barrett’s Esophagus and Esophageal Adenocarcinoma

    La Crosse, WI, Albert Lea, MN, Austin, MN, Eau Claire, WI, Mankato, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. A Study of Endolumenal Functional Lumen Imaging Probe (EndoFLIP) for Gastroesophageal Reflux Disease after Laparoscopic Sleeve Gastrectomy

    Rochester, MN

  8. Achalasia Patient Reported Outcomes

    Rochester, MN

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