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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-5 of 5 for Primary sclerosing cholangitis

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  • Study status: Open/Status Unknown
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  1. Treating Adult Patients with Primary Sclerosing Cholangitis with Oral Vancomycin in a Randomized Trial

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. Biobank for Cholestatic Liver Diseases

    Rochester, MN

  3. Pathobiology of Hepatic Epithelia: Prospective Tissue Collection

    Rochester, MN

  4. Metabolomics of Portal Venous Blood for the Study of the Gut-liver Axis in Hepatobiliary Disease

    Rochester, MN

  5. Characterization of Biliary Cell-derived Organoids from Bile of PSC and Non-PSC Patients

    Rochester, MN

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