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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 13 for Mild cognitive impairment (MCI)

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate the Safety and Effectiveness of Gantenerumab in Participants With Early Alzheimer's Disease (AD)

    Scottsdale/Phoenix, AZ

  2. A Study to Evaluate the Cognitive Effects of Oral p38 Alpha Kinase Inhibitor Neflamapimod in Dementia with Lewy Bodies

    Rochester, MN

  3. A Study to Address End-of-Life Disparities Among African Americans with Mild Cognitive Impairment and Dementia

    Jacksonville, FL

  4. A Study Evaluating the Use of 48-hour Ambulatory EEG Monitoring in Early Onset Alzheimer’s Disease

    Jacksonville, FL

  5. A Study to Evaluate Presbycusis and Presbyvestibulopathy and Risk for Mild Cognitive Impairment and Dementia

    Jacksonville, FL

  6. Advanced Care Planning in Dementia

    Jacksonville, FL

  7. Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Protocol

    Jacksonville, FL, Rochester, MN

  8. A Study to Evaluate the Effects of Voice Therapy on Cognition in the Geriatric Population

    Jacksonville, FL

  9. Mayo Alzheimer's Disease Research Center

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Cerebrospinal Fluid (CSF) Biomarkers for Prediction of Dementia

    Jacksonville, FL, Rochester, MN

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