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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 33 for

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  1. A Study of HFB200301 in Adult Patients With Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. A Safety and Efficacy Study of Domvanalimab + Zimberelimab Combination Therapy in Participants With Advanced Upper Gastrointestinal Tract Malignancies

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  3. Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

    Rochester, MN

  4. A Study of Intravital Microscopy (IVM) in Human Solid Tumors

    Jacksonville, FL

  5. A Safety Study of SEA-TGT in Patients With Advanced Cancer

    Rochester, MN

  6. Study of RP-6306 With FOLFIRI in Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Rochester, MN

  7. A Study of PY314 in Subjects With Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. A Study of Sonidegib and Pembrolizumab in Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  10. Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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