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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study to Evaluate Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Patients

    Rochester, MN

  2. A Study to Determine the Effectiveness of Early Intensive vs. Escalation Approach to Treat Relapsing/Remitting Multiple Sclerosis

    Rochester, MN

  3. A Study to Evaluate Sex Differences in Multiple Sclerosis Spectrum of Demyelinating Disorders

    Rochester, MN

  4. A Study to Evaluate 7T Magnetic Resonance Imaging in Multiple Sclerosis

    Rochester, MN


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