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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-7 of 7 for Multiple sclerosis

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  • Study status: Open/Status Unknown
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  1. A Study to Evaluate Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Patients

    Rochester, MN

  2. A Study to Analyze SAR442168 in Participants with Nonrelapsing Secondary Progressive Multiple Sclerosis

    Rochester, MN

  3. A Study to Evaluate Sex Differences in Multiple Sclerosis Spectrum of Demyelinating Disorders

    Rochester, MN

  4. A Study to Evaluate 7T Magnetic Resonance Imaging in Multiple Sclerosis

    Rochester, MN

  5. A Study to Better Understand if Diet and Metabolism are Connected with MS Relapses and Disease Progress in Patients with Pediatric-onset MS

    Rochester, MN

  6. A Study to Evaluate Patient-Family Views on Pediatric MS Research Needs, Outcomes, and Methods

    Rochester, MN

  7. MRI Markers in Multiple Sclerosis

    Rochester, MN

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