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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 11-20 of 32 for Diabetes

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  • Study status: Open/Status Unknown
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  1. Penile Length Restoration in Men with Type II Diabetes

    Rochester, MN

  2. A Study to Evaluate the Performance of an Advanced Algorithm with CGM in Adults, Adolescents, and Pediatrics

    Rochester, MN

  3. Inflammation and Stem Cells in Diabetic and Chronic Kidney Disease

    Rochester, MN

  4. Dapagliflozin in Type 2 Diabetes or Pre-diabetes, and PRESERVED Ejection Fraction Heart Failure

    Rochester, MN

  5. Effects of Niacin on FFA in UBO and T2DM in Insulin Resistant States

    Rochester, MN

  6. Effect of Improving Glycemic Control on Gastric Emptying in Type 1 and Type 2 Diabetes Mellitus

    Rochester, MN

  7. Study to Assess Painful Diabetic Peripheral Neuropathy After High-frequency Spinal Cord Stimulation

    Rochester, MN

  8. A Study to Compare Model Predictive Control (MPC) Artificial Pancreas vs. Sensor Augmented Pump (SAP)/Predictive Low Glucose Suspend (PLGS) with Different Stress Assessments for Type 1 Diabetes Patients

    Rochester, MN

  9. A Study to Evaluate How Semaglutide Works Compared to Placebo in People with Type 2 Diabetes and Chronic Kidney Disease

    Rochester, MN

  10. A Study to Evaluate the Therapeutic Effectiveness of Rifaximin in Diabetic Gastroparesis Patients Using Bloating as the Primary Endpoint

    Jacksonville, FL

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