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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 32 for Crohn's disease

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  • Study status: Open/Status Unknown
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  1. A Study of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

    Rochester, MN

  2. A Study to Assess Whether Etrolizumab is a Safe and Effective Treatment for Participants With Moderately to Severely Active Crohn's Disease (CD)

    Rochester, MN

  3. A Study of the Efficacy and Safety of Risankizumab in Participants With Crohn's Disease Who Responded to Induction Treatment in M16-006 or M15-991; or Completed M15-989

    Rochester, MN

  4. Clinical Study Comparing PillCam® Crohn's Capsule Endoscopy to Ileocolonoscopy (IC) Plus MRE for Detection of Active CD in the Small Bowel and Colon in Subjects With Known CD and Mucosal Disease

    Rochester, MN

  5. A Study of Measurable Ultrasound Imaging Biomarkers of Crohn's Disease

    Rochester, MN

  6. Study to Assess Limited Magnetic Resonance Imaging in the Surveillance of Crohn's Disease

    Rochester, MN

  7. A Study to Understand Crohn’s Disease using a Genetic Approach

    Rochester, MN

  8. A Study to Collect Biospecimens (Blood, Stool and Intestinal Biopsies) to Support the Development of Specific Biomarkers of Treatment Response to Infliximab and Vedolizumab in Children with IBD

    Rochester, MN

  9. A Study to Develop a Patient-reported Outcome Tool for Symptomatic Small Bowel Stricturing Crohn’s Disease (CD)

    Rochester, MN

  10. A Study to Develop a Registry for Outcomes and Predictors in Pouch-Related Disorders

    Rochester, MN

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