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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 30 for

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  1. Bioengineered Cardiac Tissue for Hypoplastic Left Heart Syndrome Analysis

    Rochester, MN

  2. A Study to Assess Measurements in Cardiomyopathy Patients Using Software for Multi-level Reconstruction of Three Dimensional Transesophageal Echocardiography (TEE) or Transthoracic Echocardiography (TTE) Images

    Rochester, MN

  3. Analysis of Outcomes of Left Cardiac Sympathetic Denervation in Arrhythmia Syndromes and Cardiomyopathies

    Rochester, MN

  4. Hypoplastic Left Heart Syndrome: Validating Functional Parameters and Novel Echocardiographic Imaging Strategies for Evaluation of Functionally Single Right Ventricular Performance using Previously Recorded Studies

    Rochester, MN

  5. Ventricular Remodeling and Myocardial Deformation in Patients Undergoing Chemotherapy for Sarcomas

    Rochester, MN

  6. Spontaneous Coronary Artery Dissection: Case Review

    Rochester, MN

  7. A Study to Evaluate Electrocardiogram and Heart Disease in Women

    Jacksonville, FL

  8. Stress Echo for Patients with Congenital Heart Disease

    Rochester, MN

  9. Screening for PPCM Using AI

    Jacksonville, FL, Rochester, MN

  10. A Study to Evaluate Potential Myocardial Injury Following Elective Direct Current Cardioversion

    Rochester, MN

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