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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 28 for Movement disorders

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  1. A Trial of 18F-AV-133 Positron Emission Tomography (PET) Imaging to Differentiate Subjects with Parkinson's Disease (PD) from other Movement Disorders

    Scottsdale/Phoenix, AZ

  2. Treatment of RLS/WED Symptoms Through Sensory Counter-stimulation

    Rochester, MN

  3. A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS)

    Rochester, MN

  4. A Study of the Safety, Tolerability, and Drug/Body Interactions of C2N-8E12 in People with Progressive Supranuclear Palsy

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. A Study of the Effects of Limb Cooling on Essential Tremor Using Electrophysiological Measurements

    Scottsdale/Phoenix, AZ

  6. A Phase 3 Study With P2B001 in Subjects With Early Parkinson's

    Scottsdale/Phoenix, AZ

  7. A Study of Near-Infrared Spectroscopy to Measure Brain Activity During Deep Brain Stimulation

    Rochester, MN

  8. Mobilaser Study to Help with People Who are Having Problems with Their Gait

    Jacksonville, FL

  9. A 4-Week Study of the Safety, Efficacy, and Pharmacokinetics of JZP-110 [(R)-2-amino-3-phenylpropylcarbamate Hydrochloride] in Subjects With Parkinson's Disease and Excessive Sleepiness

    Scottsdale/Phoenix, AZ

  10. A Study to Evaluate BHV-4157 in Adult Subjects with Spinocerebellar Ataxia

    Jacksonville, FL

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