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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 27 for Thyroid cancer

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  1. Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Rochester, MN

  2. Iodine I-131 With or Without Selumetinib in Treating Patients With Recurrent or Metastatic Thyroid Cancer

    Rochester, MN

  3. A Study of Selpercatinib to Treat Participants with RET-Mutant Medullary Thyroid Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. A Study of Response, Survival, Safety, and Tolerability of Lenvatinib for the Treatment of Anaplastic Thyroid Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  5. Inolitazone Dihydrochloride and Paclitaxel in Treating Patients With Advanced Anaplastic Thyroid Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  6. A Study to Test the Combination of Cabozantinib, Nivolumab, and Ipilimumab (CaboNivoIpi) for Advanced Differentiated Thyroid Cancer

    Jacksonville, FL, Rochester, MN

  7. A Study of LOXO-292 in Patients with Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  8. Pembrolizumab, Chemotherapy, and Radiation Therapy With or Without Surgery in Treating Patients With Anaplastic Thyroid Cancer

    Rochester, MN

  9. Cabozantinib-S-Malate in Treating Patients With Refractory Thyroid Cancer

    Jacksonville, FL, Rochester, MN

  10. Adequate Selection of Patients for Thyroid Biopsy: Evaluation of a Shared Decision Making Conversation Tool

    Rochester, MN

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