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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-7 of 7 for

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  1. CLEOPATTRA: A Research Study To Look At The Effects Of Treatment With A Medicine Called Coramitug (NNC6019-0001) In People With Heart Failure Due To Transthyretin Amyloid (ATTR) Amyloidosis

    Scottsdale/Phoenix, AZ

  2. MAGNITUDE: A Phase 3 Study Of NTLA-2001 In Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

    Rochester, MN

  3. TRITON-CM: A Study To Evaluate Nucresiran In Patients With Transthyretin Amyloidosis With Cardiomyopathy

    Rochester, MN

  4. Extension Study Of ACT-EARLY

    Rochester, MN

  5. To Evaluate The Long-term Safety And Tolerability Of Acoramidis In Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)

    Jacksonville, FL

  6. MAGNITUDE: A Phase 3 Study Of NTLA-2001 In Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

    Jacksonville, FL

  7. CLEOPATTRA: A Research Study To Look At The Effects Of Treatment With A Medicine Called Coramitug (NNC6019-0001) In People With Heart Failure Due To Transthyretin Amyloid (ATTR) Amyloidosis

    Rochester, MN

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