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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. A Study To Evaluate the Effect of Canakinumab or Pembrolizumab Given as Monotherapy or in Combination as Neo-adjuvant Treatment for Subjects With Early Stages NSCLC

  2. A Study to Evaluate NPC-21 to Treat Kidney Transplant Patients at High Risk for Cytomegalorvirus Infection

    Scottsdale/Phoenix, AZ

  3. Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

    Rochester, MN

  4. Effects of Long-Term Administration of Human Albumin in Subjects With Decompensated Cirrhosis and Ascites

    Scottsdale/Phoenix, AZ

  5. Patient-Reported Outcome Questionnaire for Use Among Patients with Myelofibrosis After First Line Treatment Failure

    Scottsdale/Phoenix, AZ

  6. To Compare the Effects of Immediate-release Tacrolimus and Astagraf XL on Donor-Specific Antibody (DSA) Formation and the Development of Immune Activation (IA) in de Novo Kidney Transplant Recipients

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  7. The Assessment of Prednisone In Remission Trial - Centers of Excellence Approach

    Rochester, MN

  8. Topical Composition Therapy (2013-MCN-333) for the Treatment of Melasma

    Jacksonville, FL

  9. Trial of IW-9179 in Patients With Diabetic Gastroparesis (DGP)

    Rochester, MN

  10. A Study to Evaluate Steroid-free Treatment for Standard-Risk aGVHD (BMT CTN 1501)

    Rochester, MN

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