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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  • Locations: Rochester, MN
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  1. Brightline-4: A study to test how well brigimadlin is tolerated by people with a type of cancer called dedifferentiated liposarcoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  2. Comparison of standard care with radiation and medicinal therapy vs radiation alone for prostate cancer

    Rochester, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL

  3. Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie’s Disease

    Rochester, MN

  4. Neoadjuvant Aliya™ PEF Soft Tissue Ablation With Systemic Therapy in Early-Stage Resectable NSCLC (VIGOR)

    Rochester, MN

  5. The Development and Testing of a Shared Decision Making Encounter Tool for Weight Management Decisions

    Rochester, MN, Jacksonville, FL

  6. A Study to Evaluate CC-96191 to Treat Participants With Relapsed or Refractory Acute Myeloid Leukemia

    Jacksonville, FL, Rochester, MN

  7. Tafasitamab, Lenalidomide and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma

    Rochester, MN

  8. A Study of the Combination of Talquetamab and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

    Rochester, MN

  9. Duvelisib and Nivolumab for the Treatment of Stage IIB-IVB Mycosis Fungoides and Sezary Syndrome

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. Verapamil vs. Sertraline for Vestibular Migraine & Chronic Subjective Dizziness

    Scottsdale/Phoenix, AZ, Rochester, MN

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