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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 621-630 of 7937

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  • Locations: Rochester, MN
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  1. A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer

    Rochester, MN

  2. A Study to Evaluate KD025 in Subjects with Diffuse Cutaneous Systemic Sclerosis

    Rochester, MN

  3. Fenofibrate for Prevention of DR Worsening

    Rochester, MN

  4. Arthroscopic Partial Meniscectomy in OA: A 12-Year Follow-Up

    Rochester, MN

  5. Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

    Rochester, MN

  6. Pembrolizumab Plus Epacadostat Alone or With Platinum-based Chemotherapy Versus Pembrolizumab Plus Platinum-based Chemotherapy Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-715-02/ECHO-306)

    Rochester, MN

  7. A Study to Demonstrate that Acetazolamide is not Inferior to Diazepam for Patients who have Continuous Spike and Wave Brain Pattern in Sleep

    Rochester, MN

  8. Addressing Diabetes Together

    Rochester, MN

  9. Study of the EZH2 Inhibitor Tazemetostat in Malignant Mesothelioma

    Rochester, MN

  10. Effects of Music-Assisted-Relaxation on Anxiety and Pain for Patients with Spinal-Cord Injury

    Rochester, MN

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