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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 6241-6250 of 10871

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  1. Using Ultrasound to Improve the Palpation Skills of Physicians in Training

    Rochester, MN

  2. Low-Cost Tool for Compliance and Treatment-Tracking of Low Back Pain Patients

    Rochester, MN

  3. A Study of Single Patient Investigational Drug CPI-613 for Use in Treatment-Refractory, Metastatic Prostate Cancer

    Rochester, MN

  4. Ultrasound Assessment of Weightbearing and Non-Weightbearing Meniscal Protrusion

    Rochester, MN

  5. A Study of SC-006 in Subjects With Advanced Cancer

  6. Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid Malabsorption

    Rochester, MN

  7. A Study to Use a Patient Monitoring Application that Monitors Physiological Data, Psychosocial Data, and Responses to Survey Questions in Patients Undergoing Cranial or Spinal Surgery

    Rochester, MN

  8. Subcutaneous Furosemide in Acute Decompensated Heart Failure: The SUBQ-HF Study

    Rochester, MN

  9. Ipilimumab and Nivolumab as Adjuvant Treatment of Mucosal Melanoma

    Rochester, MN

  10. Evaluation of Rate Adaptive Pacing on Chronotropic Response in Preserved Ejection Fraction HF

    Rochester, MN

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