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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. Evaluation of Dual Therapy with Dabigatran versus Triple Therapy with Warfarin in Patients with Atrial Fibrillation that Undergo a Percutaneous Coronary Intervention with Stenting (REDUAL-PCI)

    Scottsdale/Phoenix, AZ

  2. An Evaluation of the MitraClip System for treatment of Mitral Regurgitation in Heart Failure Patients

    Scottsdale/Phoenix, AZ

  3. A Study to Provide Feasibility Data for a Novel Method of Defining Patient-Specific Functional Anatomic Targets for Globus Pallidus Internus (GPi) Deep Brain Stimulation (DBS) Placement

    Jacksonville, FL

  4. Usage of EpiFinder Clinical Decision Support in the Assessment of Epilepsy Cases at Mayo Clinic Hospital in AZ

    Scottsdale/Phoenix, AZ

  5. Multinational Clinical Study Comparing Isatuximab, Pomalidomide, and Dexamethasone to Pomalidomide and Dexamethasone in Refractory or Relapsed and Refractory Multiple Myeloma Patients

    Scottsdale/Phoenix, AZ, Rochester, MN

  6. Phase II Randomized Trial of mFOLFIRINOX +/- Ramucirumab in Advanced Pancreatic Cancer

    Scottsdale/Phoenix, AZ

  7. First-in-Human Study of KO-947 in Non-Hematological Malignancies

  8. Filgotinib in Long-Term Extension Study of Adults With Ulcerative Colitis

    Rochester, MN

  9. VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM

    Rochester, MN

  10. Obinutuzumab With or Without PI3K-delta Inhibitor TGR-1202, Lenalidomide, or Combination Chemotherapy in Treating Patients With Relapsed or Refractory Grade I-IIIa Follicular Lymphoma

    Rochester, MN

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