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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors

  2. A Safety, Methodological and Exploratory Biomarkers Study to Slow Disease Progression

    Jacksonville, FL

  3. A Study to Assess the Effects of the Minnesota Medical Technologies Anal Insert Device in Fecal Incontinence

    Rochester, MN

  4. A Study to Evaluate Using Interactive Video Games in Treating Adults with Amblyopia

    Rochester, MN

  5. ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

    Rochester, MN

  6. Bevacizumab with or without Anti-Endoglin Monoclonal Antibody TRC105 in Treating Patients with Recurrent Glioblastoma Multiforme

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  7. SGI-110 in Patients with Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML)

    Scottsdale/Phoenix, AZ

  8. A Study of Oral Sapacitabine in Elderly Patients with Newly Diagnosed Acute Myeloid Leukemia

    Rochester, MN

  9. Study of Dexamethasone Plus IXAZOMIB or Physician's Choice of Treatment in Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis

    Rochester, MN

  10. Alisertib (MLN8237) or Investigator's Choice in Patients With Relapsed/Refractory Peripheral T-Cell Lymphoma

    Rochester, MN

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