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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 5351-5360 of 10980

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  1. A Study of the Safety and Effectiveness of JZP-110 in the Treatment of Excessive Sleepiness in Patients with Narcolepsy

    Scottsdale/Phoenix, AZ

  2. A Study to Evaluate Pembrolizumab for Surgically Treated Adjuvant Merkel Cell Carcinoma

    Eau Claire, WI, Rochester, MN

  3. A Study to Evaluate the Safety and Effectiveness of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy

    Rochester, MN

  4. Azacitidine With or Without Nivolumab or Midostaurin, or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

    Rochester, MN

  5. A Study to Assess the Safety and Effectiveness of FLX-787 in Subjects With Charcot-Marie-Tooth Disease Experiencing Muscle Cramps.

  6. d68Ga-DOTATATE PET/CT Assessment of Cardiac Sarcoidosis

    Rochester, MN

  7. A Study of Gemcitabine-Cisplatin Chemotherapy plus Necitumumab in the First-Line Treatment of Patients with Lung Cancer

    Scottsdale/Phoenix, AZ

  8. A Study of Pembrolizumab Alone or Combined with CC-486 for Patients with Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer

    Rochester, MN

  9. A Study to Evaluate Remicade (Infliximab) for the Prevention of Recurrence in Crohn's Disease Patients Undergoing Surgical Resection and are at an Increased Risk of Recurrence

    Rochester, MN

  10. A Study to Evaluate the Effectiveness and Safety of P276-00 for Mantle Cell Lymphoma that has Returned and/or is Resistant to Treatment

    Scottsdale/Phoenix, AZ, Rochester, MN

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