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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 5181-5190 of 10866

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  1. Real-Time Myocardial Perfusion Echocardiography in the ICU

    Rochester, MN

  2. Trial of Intravesical Measles Virotherapy in Patients With Bladder Cancer Who Are Undergoing Radical Cystectomy

    Jacksonville, FL, Rochester, MN

  3. A Study to Evaluate the Efficacy and Safety of Oxabact in Patients With Primary Hyperoxaluria

    Rochester, MN

  4. A Study of the Safety And Effectiveness of Palbociclib Plus Cetuximab versus Cetuximab Alone to Treat Head and Neck Cancer

    Rochester, MN

  5. Addressing Sleep Problems in Older Adults

    Rochester, MN

  6. Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma

  7. Efficacy and Safety Trial of RPC1063 for Moderate to Severe Crohn's Disease

    Rochester, MN

  8. Long-term Safety and Tolerability of Atacicept (Long-term Follow-Up of Patients Who Participated in ADDRESS II)

    Rochester, MN

  9. A Study to Investigate the Effectiveness and Safety of Cannabidiol in Children and Young Adults with Dravet Syndrome

    Rochester, MN

  10. Evaluation of ALD403 (Eptinezumab) in the Prevention of Chronic Migraine

    Scottsdale/Phoenix, AZ

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