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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. Ascorbic Acid and Combination Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma or CCUS

    Rochester, MN, La Crosse, WI, Eau Claire, WI, Mankato, MN

  2. A Study to Treat Patients with Dravet Syndrome Using ZX008

    Rochester, MN

  3. The Effect of Blenderized Tube Feeding on Enteral Nutrition Tolerance and the Gut Microbiome

    Rochester, MN

  4. Ipilimumab With or Without Talimogene Laherparepvec in Unresected Melanoma

  5. Efficacy and Safety Trial of Conbercept Intravitreal Injection for Neovascular Age-related Macular Degeneration (PANDA-1)

    Jacksonville, FL

  6. Evaluation of Safety and Efficacy of Allo GDA-201 NK Cells in Patients With Relapsed/Refractory B Cell NHL

    Jacksonville, FL

  7. Dose Escalation Study of mRNA 2416 for Intratumoral Injection to Patients With Advanced Malignancies

    Scottsdale/Phoenix, AZ

  8. A Study of AK002 in Patients with Eosinophilic Gastritis and/or Eosinophilic Gastroenteritis

    Scottsdale/Phoenix, AZ, Rochester, MN

  9. A Study to Evaluate Increased Prevalence of Esophageal Motility Disorders Following Bariatric Surgery

    Rochester, MN

  10. A Study to Evaluate Dapagliflozin to Improve the LIVEs of Patients With PReserved Ejection Fraction Heart Failure

    Rochester, MN

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