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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. Comparison Of Acute Toxicities Between Patients Treated With Protons Or Intensity Modulated Radiation Therapy After Surgery For The Treatment Of Endometrial Or Cervical Cancer

    Albert Lea, MN, Scottsdale/Phoenix, AZ, Eau Claire, WI, Jacksonville, FL, La Crosse, WI, Mankato, MN, Rochester, MN

  2. MAGNITUDE: A Phase 3 Study Of NTLA-2001 In Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

    Jacksonville, FL

  3. Study Of Tirabrutinib (ONO-4059) In Patients With Primary Central Nervous System Lymphoma (PROSPECT Study)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  4. REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities

    Scottsdale/Phoenix, AZ

  5. Acquisition of Fetal ECG with Intact Membranes

  6. Senescence In Chronic Kidney Disease

    Jacksonville, FL, Rochester, MN

  7. Study Of TL-895 In Subjects With Myelofibrosis Or Indolent Systemic Mastocytosis

    Scottsdale/Phoenix, AZ, Rochester, MN

  8. A Study To Investigate Efficacy & Safety Of Intratumoral INT230-6 Compared To US Standard Of Care In Adults With Soft Tissue Sarcomas (INVINCIBLE-3)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  9. A Study Testing The Effect Of Immunotherapy (Ipilimumab And Nivolumab) In Patients With Recurrent Glioblastoma With Elevated Mutational Burden

    Scottsdale/Phoenix, AZ, Eau Claire, WI, Jacksonville, FL, La Crosse, WI, Rochester, MN

  10. Privosegtor Investigation In Optic Neuropathies Efficacy Evaluation Research (PIONEER #1)

    Rochester, MN

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